Liu N, Li H, Liu H W, Wang Z Q, Zheng Y
Department of Otorhinolaryngology, the Second Affiliated Hospital of Xinjiang Medical University, Urumqi, 830063, China.
Department of Otorhinolaryngology, the Fifth Affiliated Hospital of Xinjiang Medical University.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Jun;33(6):549-552. doi: 10.13201/j.issn.1001-1781.2019.06.018.
To investigate the relationship between red blood cell distribution width (RDW) and severity of obstructive sleep apnea hypopnea syndrome (OSAHS). A total of 112 patients with OSAHS who were diagnosed by PSG monitoring were selected as OSAHS group, and 61 healthy subjects with matched age, gender and BMI were selected as the control group. The peripheral venous blood of all subjects was collected in the morning, and relevant hematological indexes such as RDW, white blood cell count, red blood cell count, hemoglobin, mean red blood cell volume, and platelet count were obtained. The RDW level in the OSAHS group was significantly higher than that in the control group. The RDW value increased gradually with the severity of OSAHS and was positively correlated with AHI(=0.259), the mean SaO₂ (=-0.279), the lowest SaO₂( =-0.328), BMI(=0.203) and negatively correlated with sleep time(=-0.204). The elevated level of RDW may be an indicator of the severity of OSAHS. Since RDW is usually included in the complete blood count, it can provide an economical and practical indicator to initially assess the condition of OSAHS patients and prioritize polysomnography monitoring.
探讨红细胞分布宽度（RDW）与阻塞性睡眠呼吸暂停低通气综合征（OSAHS）严重程度之间的关系。选取112例经多导睡眠图（PSG）监测确诊的OSAHS患者作为OSAHS组，选取61例年龄、性别和体重指数（BMI）相匹配的健康受试者作为对照组。所有受试者于清晨采集外周静脉血，检测RDW、白细胞计数、红细胞计数、血红蛋白、平均红细胞体积和血小板计数等相关血液学指标。OSAHS组的RDW水平显著高于对照组。RDW值随OSAHS严重程度的增加而逐渐升高，与呼吸暂停低通气指数（AHI）（=0.259）、平均血氧饱和度（SaO₂）（=-0.279）、最低血氧饱和度（=-0.328）、BMI（=0.203）呈正相关，与睡眠时间（=-0.204）呈负相关。RDW水平升高可能是OSAHS严重程度的一个指标。由于RDW通常包含在血常规检查中，它可以为初步评估OSAHS患者的病情并确定多导睡眠图监测的优先级提供一个经济实用的指标。
