Department of Epidemiology, School of Public Health, China Medical University, Shenyang, China.
Department of Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, China.
BMC Infect Dis. 2019 Jun 4;19(1):494. doi: 10.1186/s12879-019-4138-5.
A high proportion of men who have sex with men (MSM) use geosocial networking apps (Apps) to seek partners. However, the relationship of app use with HIV risk is unknown. Further, the risks of some sexually transmitted infection (STIs), including Mycoplasma genitalium, have seldom been studied among MSM.
MSM were enrolled at a community-based HIV testing site in Shenyang, China. After completing a questionnaire survey, we collected rectal swabs and venous blood specimens. We then simultaneously tested for ten STIs (Chlamydia trachomatis [CT], Neisseria gonorrhea [NG], Ureaplasma urealyticum [Uu], Ureaplasma parvum species [Up1, Up3, Up6, Up14), Mycoplasma hominis [Mh], Mycoplasma genitalium [Mg], and Herpes Simplex Virus Type 2 (HSV-2) using multiple PCR. We also performed blood tests for HIV, Syphilis, Hepatitis C antibody (HCV-Ab), Hepatitis B Surface Antigen (HBsAg), and Hepatitis A-IgM (HAV-IgM), etc. RESULTS: One hundred and eighty-three MSM participated in this study, of which 51.4% reported seeking partners through apps in the past year. The prevalence of HIV was 19.7%, Syphilis 12.0%, HAV 1.1%, rectal Mg 15.3% and Mh 7.1%. Multivariable logistic regression showed that HIV infection was independently correlated with app-using behavior (adjusted odds ratio[aOR] = 2.6), Mg infection (aOR = 3.2), Mh infection (aOR = 4.1) and Syphilis infection (aOR = 3.1) (each P < 0.05).
App use, Mg, Mh and Syphilis infection were correlated with higher HIV Risk in MSM. Geosocial networking apps should be utilized for HIV interventions targeting MSM. There is a need for more expansive STIs screening, particularly for Mg, Mh and Syphilis in MSM.
相当一部分男男性行为者（MSM）使用基于地理位置的社交网络应用程序（Apps）来寻找性伴侣。然而，应用程序的使用与 HIV 风险之间的关系尚不清楚。此外，包括支原体属在内的一些性传播感染（STI）的风险在 MSM 中很少被研究。
在沈阳市一个基于社区的 HIV 检测点招募了 MSM。在完成问卷调查后，我们采集了直肠拭子和静脉血标本。然后，我们使用多重 PCR 同时检测了十种 STI（沙眼衣原体 [CT]、淋病奈瑟菌 [NG]、解脲脲原体 [Uu]、解脲脲原体种 [Up1、Up3、Up6、Up14]、人型支原体 [Mh]、生殖支原体 [Mg] 和单纯疱疹病毒 2 型 [HSV-2]）。我们还进行了 HIV、梅毒、丙型肝炎抗体（HCV-Ab）、乙肝表面抗原（HBsAg）和甲型肝炎 IgM（HAV-IgM）等血液检测。
183 名 MSM 参与了这项研究，其中 51.4%的人报告在过去一年中通过应用程序寻找性伴侣。HIV 感染率为 19.7%，梅毒 12.0%，甲型肝炎 1.1%，直肠 Mg 感染率为 15.3%，Mh 感染率为 7.1%。多变量 logistic 回归显示，HIV 感染与应用程序使用行为（调整后比值比[aOR] = 2.6）、Mg 感染（aOR = 3.2）、Mh 感染（aOR = 4.1）和梅毒感染（aOR = 3.1）独立相关（均 P < 0.05）。
应用程序使用、Mg、Mh 和梅毒感染与 MSM 中的 HIV 风险增加相关。基于地理位置的社交网络应用程序应被用于针对 MSM 的 HIV 干预。需要更广泛地筛查 STI，特别是 MSM 中的 Mg、Mh 和梅毒。
