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UCSC 基因组浏览器数据库:2018 年更新。

The UCSC Genome Browser database: 2018 update.

机构信息

Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA.

Howard Hughes Medical Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA.

出版信息

Nucleic Acids Res. 2018 Jan 4;46(D1):D762-D769. doi: 10.1093/nar/gkx1020.

Abstract

The UCSC Genome Browser (https://genome.ucsc.edu) provides a web interface for exploring annotated genome assemblies. The assemblies and annotation tracks are updated on an ongoing basis-12 assemblies and more than 28 tracks were added in the past year. Two recent additions are a display of CRISPR/Cas9 guide sequences and an interactive navigator for gene interactions. Other upgrades from the past year include a command-line version of the Variant Annotation Integrator, support for Human Genome Variation Society variant nomenclature input and output, and a revised highlighting tool that now supports multiple simultaneous regions and colors.

摘要

UCSC 基因组浏览器(https://genome.ucsc.edu)提供了一个用于浏览注释基因组组装的网络界面。组装和注释轨道在不断更新-在过去的一年中添加了 12 个组装和超过 28 个轨道。最近的两个新增功能是显示 CRISPR/Cas9 引导序列和基因相互作用的交互式导航器。去年的其他升级包括 Variant Annotation Integrator 的命令行版本、对人类基因组变异协会变异命名法输入和输出的支持,以及修订后的突出显示工具,现在支持多个同时的区域和颜色。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3976/5753355/1d64ca8b368e/gkx1020fig1.jpg

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