Department of Otorhinolaryngology-Head and Neck Surgery, HUS Helsinki University Hospital, University of Helsinki, P.O.Box 263, FI-00029 HUS Helsinki, Finland.
Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
Int J Environ Res Public Health. 2021 Jan 21;18(3):911. doi: 10.3390/ijerph18030911.
Better visualization of tumor structure and orientation are needed in the postoperative setting. We aimed to assess the feasibility of a system in which oral and oropharyngeal tumors are resected, photographed, 3D modeled, and printed using additive manufacturing techniques. Three patients diagnosed with oral/oropharyngeal cancer were included. All patients underwent preoperative magnetic resonance imaging followed by resection. In the operating room (OR), the resected tissue block was photographed using a smartphone. Digital photos were imported into Agisoft Photoscan to produce a digital 3D model of the resected tissue. Physical models were then printed using binder jetting techniques. The aforementioned process was applied in pilot cases including carcinomas of the tongue and larynx. The number of photographs taken for each case ranged from 63 to 195. The printing time for the physical models ranged from 2 to 9 h, costs ranging from 25 to 141 EUR (28 to 161 USD). Digital photography may be used to additively manufacture models of resected oral/oropharyngeal tumors in an easy, accessible and efficient fashion. The model may be used in interdisciplinary discussion regarding postoperative care to improve understanding and collaboration, but further investigation in prospective studies is required.
在术后环境中，需要更好地可视化肿瘤结构和方向。我们旨在评估一种系统的可行性，该系统可用于切除、拍摄、3D 建模和使用增材制造技术打印口腔和口咽肿瘤。纳入了 3 名诊断为口腔/口咽癌的患者。所有患者均接受术前磁共振成像检查，然后进行切除。在手术室 (OR) 中，使用智能手机拍摄切除的组织块的照片。数字照片导入 Agisoft Photoscan 以生成切除组织的数字 3D 模型。然后使用粘结剂喷射技术打印物理模型。上述过程应用于包括舌癌和喉癌在内的试点案例。每个病例拍摄的照片数量从 63 到 195 不等。物理模型的打印时间从 2 到 9 小时不等，成本从 25 到 141 欧元（28 到 161 美元）不等。数字摄影可用于以简单、可访问和高效的方式制造切除的口腔/口咽肿瘤的模型。该模型可用于涉及术后护理的跨学科讨论，以提高理解和协作，但需要进一步进行前瞻性研究。
