Wreghitt T G, Sillis M
Clinical Microbiology and Public Health Laboratory, Addenbrooke's Hospital, Cambridge, UK.
Isr J Med Sci. 1987 Jun;23(6):704-8.
The mu-capture, the ELISA, IF and CF tests were used to study Mycoplasma pneumoniae infections in Cambridge in 1983. We studied 393 samples of serum submitted for investigation of M. pneumoniae infection, from 298 patients. There was a good correlation between mu-capture ELISA and IF for detecting M. pneumoniae-specific IgM, and between elevated CF titer, and the presence of M. pneumoniae-specific IgM. There was also a clear correlation between M. pneumoniae-specific IgM status and age. M. pneumoniae-specific IgM and IgA were most often found together in sera, but in some sera, only one of these antibodies was found at significant levels. These findings were not age related, and thus not obviously useful in differentiating primary and recurrent M. pneumoniae infections.
1983年，采用μ捕获法、酶联免疫吸附测定（ELISA）、免疫荧光法（IF）和补体结合试验（CF）对剑桥地区的肺炎支原体感染情况进行了研究。我们研究了298例患者提交的393份用于肺炎支原体感染调查的血清样本。在检测肺炎支原体特异性IgM方面，μ捕获ELISA法与免疫荧光法之间存在良好的相关性；在补体结合滴度升高与肺炎支原体特异性IgM的存在之间也存在良好的相关性。肺炎支原体特异性IgM状态与年龄之间也存在明显的相关性。肺炎支原体特异性IgM和IgA最常同时出现在血清中，但在某些血清中，仅发现其中一种抗体处于显著水平。这些发现与年龄无关，因此在区分原发性和复发性肺炎支原体感染方面没有明显用处。
