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伴有皮下转移的晚期食管肿瘤

Advanced Esophageal Neoplasm with Subcutaneous Metastasis.

作者信息

de Oliveira Rivadávio A M, da Silva Tassiara, Piovesana Mariana Miyasaki, Stecca Carlos Eduardo, Lopes George A, Liutti Vitor Teixeira

机构信息

Department of Clinical Oncology at the Hospital do Câncer de Londrina, Brazil.

Department of Pathology Anatomy at the Hospital do Câncer de Londrina, Brazil.

出版信息

Case Rep Oncol Med. 2019 Apr 24;2019:9103137. doi: 10.1155/2019/9103137. eCollection 2019.

Abstract

OBJECTIVE

This report is aimed at describing a rare clinical condition of advanced esophageal cancer with subcutaneous metastasis.

CASE REPORT

The present case refers to a patient diagnosed with stage IV esophageal squamous cell carcinoma which started with dysphonia and cervical nodules. Soon after that, the patient developed dysphagia and subcutaneous lesions on the right flank. Later in time, we documented a disease progression, with worsening of subcutaneous implants, lymph node, bone, and pulmonary metastases in addition to malignant hypercalcemia.

CONCLUSION

This illustrates a rare presentation of an advanced esophageal neoplasm. Subcutaneous metastasis from internal malignancies is unusual, corresponding to less than 10% of cases. Its occurrence in patients with esophageal cancer is even less common with very few cases reported in literature.

摘要

目的

本报告旨在描述晚期食管癌伴皮下转移这一罕见临床情况。

病例报告

本病例为一名被诊断为IV期食管鳞状细胞癌的患者,最初表现为声音嘶哑和颈部结节。此后不久,患者出现吞咽困难及右侧胁腹皮下病变。随后,我们记录到疾病进展,皮下植入物、淋巴结、骨及肺转移恶化,此外还出现了恶性高钙血症。

结论

这例晚期食管肿瘤表现罕见。内脏恶性肿瘤的皮下转移并不常见,占病例不到10%。其在食管癌患者中更为罕见,文献报道的病例极少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1fc/6507115/83023c89b0df/CRIONM2019-9103137.001.jpg

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