使用直线加速器进行体外放射生物学实验。
Use of a Linear Accelerator for Conducting In Vitro Radiobiology Experiments.
作者信息
Hao Jing, Magnelli Anthony, Godley Andrew, Yu Jennifer S
机构信息
Department of Cancer Biology, Cleveland Clinic.
Department of Radiation Oncology, Cleveland Clinic.
出版信息
J Vis Exp. 2019 May 26(147). doi: 10.3791/59514.
Abstract
Radiation therapy remains one of the cornerstones of cancer management. For most cancers, it is the most effective, nonsurgical therapy to debulk tumors. Here, we describe a method to irradiate cancer cells with a linear accelerator. The advancement of linear accelerator technology has improved the precision and efficiency of radiation therapy. The biological effects of a wide range of radiation doses and dose rates continue to be an intense area of investigation. Use of linear accelerators can facilitate these studies using clinically relevant doses and dose rates.
摘要
放射治疗仍然是癌症治疗的基石之一。对于大多数癌症来说，它是最有效的非手术肿瘤减容疗法。在此，我们描述一种使用直线加速器照射癌细胞的方法。直线加速器技术的进步提高了放射治疗的精度和效率。广泛的辐射剂量和剂量率的生物学效应仍然是一个深入研究的领域。使用直线加速器可以利用临床相关的剂量和剂量率来促进这些研究。
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