Funmap2: an R package for QTL mapping using longitudinal phenotypes.

Quantitative trait locus (QTL) mapping has been used as a powerful tool for inferring the complexity of the genetic architecture that underlies phenotypic traits. This approach has shown its unique power to map the developmental genetic architecture of complex traits by implementing longitudinal data analysis. Here, we introduce the R package based on the functional mapping framework, which integrates prior biological knowledge into the statistical model. Specifically, the functional mapping framework is engineered to include longitudinal curves that describe the genetic effects and the covariance matrix of the trait of interest. chooses the type of longitudinal curve and covariance matrix automatically using information criteria. is available for download at https://github.com/wzhy2000/Funmap2.