Zhang Wenxiao, Xu Cui, Li Rui, Cui Guanghe, Wang Minmin, Wang Min
Department of Ultrasound Medicine, Binzhou Medical University Hospital, Binzhou, Shandong 256600, P.R. China.
Department of Health Management, Binzhou Medical University Hospital, Binzhou, Shandong 256600, P.R. China.
Oncol Lett. 2019 Jun;17(6):5511-5516. doi: 10.3892/ol.2019.10246. Epub 2019 Apr 12.
Value and correlation analysis between ultrasound and mammography in the diagnosis and other risk factors related to breast cancer were explored. A total of 1,473 patients who underwent breast color ultrasonography and molybdenum target X-ray examination in Binzhou Medical University Hospital from March 2017 to August 2018 were collected, and the patient's ultrasound and mammography results were compared, also the pathological biopsy was used as the reference golden criteria to calculate the value of both test methods and the value of combined diagnosis in breast cancer. The risk factors associated with breast cancer were analyzed. Among the 1,473 patients, 387 breast cancer patients were detected by ultrasonography, 351 by mammography and 339 cases by combined diagnosis. A total of 314 cases were diagnosed as breast cancer after pathological biopsy. However, there were significant differences in tumor size, stages, and BI-RADS grades (P<0.05). There was no significant difference in the diagnostic efficacy between ultrasonography and mammography (P>0.05), however, the diagnostic efficacy of ultrasonography combined with mammography was significantly better than the two single tests (P<0.05). After logistic regression analysis, there was no significant correlation between residence address, height, blood type, ethnicity, or education with breast cancer (P>0.05). However, age, fertility status, and BMI were all risk factors related to breast cancer (OR>1; P<0.05). In conclusion, ultrasonography combined with mammography can effectively improve the early diagnosis rate of breast cancer, however, the patient's age, birth status, and BMI may affect the results of ultrasonography and mammography. In clinical practice, it is necessary to determine the imaging results in combination with the actual situation of the patients to improve the diagnosis rate of breast cancer.
探讨超声与乳腺钼靶在乳腺癌诊断及其他相关危险因素中的价值及相关性分析。收集2017年3月至2018年8月在滨州医学院附属医院接受乳腺彩色超声检查和钼靶X线检查的1473例患者，比较患者的超声和钼靶检查结果，并以病理活检作为参考金标准，计算两种检查方法及联合诊断在乳腺癌中的价值。分析与乳腺癌相关的危险因素。在1473例患者中，超声检查发现387例乳腺癌患者，钼靶检查发现351例，联合诊断发现339例。经病理活检确诊为乳腺癌的共314例。然而，肿瘤大小、分期和BI-RADS分级存在显著差异（P<0.05）。超声与钼靶的诊断效能无显著差异（P>0.05），但超声联合钼靶的诊断效能明显优于两种单项检查（P<0.05）。经逻辑回归分析，居住地址、身高、血型、种族或教育程度与乳腺癌无显著相关性（P>0.05）。然而，年龄、生育状况和BMI均为与乳腺癌相关的危险因素（OR>1；P<0.05）。总之，超声联合钼靶可有效提高乳腺癌的早期诊断率，然而，患者的年龄、生育状况和BMI可能会影响超声和钼靶的检查结果。在临床实践中，有必要结合患者的实际情况来判断影像学检查结果，以提高乳腺癌的诊断率。
