Cirstoiu Catalin, Cretu Bogdan, Serban Bogdan, Panti Zsombor, Nica Mihai
Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania.
University Emergency Hospital Bucharest, Romania.
EFORT Open Rev. 2019 May 10;4(5):174-182. doi: 10.1302/2058-5241.4.180048. eCollection 2019 May.
Modern surgical management of extremity bone sarcomas is governed by limb-sparing surgery combined with adjuvant and neoadjuvant chemotherapy.All the resection and reconstruction techniques have to achieve oncologic excision margins, with survival rates and functional results superior to amputation.The main reconstruction techniques of bone defects resulted after resection are: modular endoprosthetic reconstruction; bone graft reconstruction; bone transport; resection arthrodesis; and rotationplasty.Oncologic resection and modular endoprosthetic reconstruction are the generally approved surgical options adopted for the majority of cases in major specialized bone sarcoma centres.Good basic principles, efficient multidisciplinary approach and sustained research in the field can provide a better future for the challenge posed by extremity bone sarcoma treatment. Cite this article: 2019;4:174-182. DOI: 10.1302/2058-5241.4.180048.
肢体骨肉瘤的现代外科治疗方法是保肢手术联合辅助化疗和新辅助化疗。所有的切除和重建技术都必须达到肿瘤学切除边界，其生存率和功能结果优于截肢术。切除术后骨缺损的主要重建技术包括：模块化人工关节假体重建；骨移植重建；骨搬运；切除关节融合术；以及旋转成形术。肿瘤切除和模块化人工关节假体重建是大多数主要专业骨肉瘤中心对大多数病例普遍认可采用的手术选择。良好的基本原则、有效的多学科方法以及该领域持续的研究能够为肢体骨肉瘤治疗所带来的挑战提供更美好的未来。引用本文：2019;4:174 - 182。DOI: 10.1302/2058 - 5241.4.180048。
