Ring Andrej, Kirchhoff Pascal, Goertz Ole, Behr Bjorn, Daigeler Adrien, Lehnhardt Marcus, Harati Kamran
Department for Plastic and Hand Surgery, Burn Center/Sarcoma Reference Center, Ruhr-University Bochum , Bochum , Germany.
Front Surg. 2016 Mar 8;3:15. doi: 10.3389/fsurg.2016.00015. eCollection 2016.
Solid malignancies at the foot and ankle region are rare and include mainly soft-tissue sarcomas, bone sarcomas, and skin malignancies. Complete surgical resection with clear margins still remains the mainstay of therapy in these malignancies. However, attainment of negative surgical margins in patients with locally advanced tumors of the foot and ankle region may require extensive surgery and could result in loss of extremity function. In these circumstances, plastic surgical techniques can frequently reduce functional impairment and cover soft-tissue defects, particularly in cases of large tumor size or localization adjacent to critical anatomic structures, thereby improving the quality of life for these patients. The aim of this article is to illustrate the various treatment options of plastic surgery in the multimodal therapy of patients with malignant tumors of the foot and ankle region.
This article is based on the review of the current literature and the evaluation of the author's own patient database.
The local treatment of malignant extremity tumors has undergone major changes over the last few decades. Primary amputations have been increasingly replaced by limb-sparing techniques, preserving extremity function as much as possible. Although defect coverage at the foot and ankle region is demanding due to complex anatomical features and functional requirements, several plastic surgical treatment options can be implemented in the curative treatment of patients with malignant solid tumors in this area. Soft-tissue defects after tumor resection can be covered by a variety of local flaps. If local flaps are not applicable, free flap transfers, such as the anterolateral thigh flap, parascapular flap, or latissimus dorsi flap, can be utilized to cover nearly all kinds of defects in the foot and ankle region.
Soft-tissue reconstruction in the foot and ankle region is a vital component of limb-sparing surgery. It enables complete resection of locally advanced tumors and subsequent adjuvant radiotherapy. Modern plastic surgical techniques should, therefore, be integrated in the multimodal treatment concept of malignancies in the foot and ankle region.
足踝部实体恶性肿瘤较为罕见,主要包括软组织肉瘤、骨肉瘤和皮肤恶性肿瘤。手术切缘阴性的完整手术切除仍是这些恶性肿瘤治疗的主要手段。然而,对于足踝部局部晚期肿瘤患者,要实现手术切缘阴性可能需要进行广泛手术,这可能导致肢体功能丧失。在这些情况下,整形外科技术常常可以减少功能障碍并覆盖软组织缺损,特别是在肿瘤体积大或位于关键解剖结构附近的病例中,从而改善这些患者的生活质量。本文旨在阐述整形外科在足踝部恶性肿瘤多模式治疗中的各种治疗选择。
本文基于对当前文献的综述以及对作者自身患者数据库的评估。
在过去几十年中,肢体恶性肿瘤的局部治疗发生了重大变化。一期截肢已越来越多地被保肢技术所取代,尽可能保留肢体功能。尽管由于足踝部复杂的解剖特征和功能需求,缺损覆盖颇具挑战性,但在该区域实体恶性肿瘤患者的根治性治疗中,可以采用多种整形外科治疗选择。肿瘤切除后的软组织缺损可用多种局部皮瓣覆盖。如果局部皮瓣不适用,可采用游离皮瓣移植,如股前外侧皮瓣、肩胛旁皮瓣或背阔肌皮瓣,以覆盖足踝部几乎所有类型的缺损。
足踝部软组织重建是保肢手术的重要组成部分。它能够完整切除局部晚期肿瘤并进行后续辅助放疗。因此,现代整形外科技术应融入足踝部恶性肿瘤的多模式治疗理念中。