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本文引用的文献

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HIV Preexposure Prophylaxis, by Race and Ethnicity - United States, 2014-2016.HIV 暴露前预防,按种族和族裔划分-美国,2014-2016 年。
MMWR Morb Mortal Wkly Rep. 2018 Oct 19;67(41):1147-1150. doi: 10.15585/mmwr.mm6741a3.
2
The prevalence of pre-exposure prophylaxis use and the pre-exposure prophylaxis-to-need ratio in the fourth quarter of 2017, United States.2017 年第四季度美国暴露前预防用药的使用情况和暴露前预防用药的需求比。
Ann Epidemiol. 2018 Dec;28(12):841-849. doi: 10.1016/j.annepidem.2018.06.005. Epub 2018 Jun 15.
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Integrating HIV Preexposure Prophylaxis (PrEP) Into Routine Preventive Health Care to Avoid Exacerbating Disparities.将艾滋病病毒暴露前预防(PrEP)纳入常规预防性医疗保健以避免加剧差异。
Am J Public Health. 2017 Dec;107(12):1883-1889. doi: 10.2105/AJPH.2017.304061. Epub 2017 Oct 19.
4
The Transgender Women of Color Initiative: Implementing and Evaluating Innovative Interventions to Enhance Engagement and Retention in HIV Care.有色人种跨性别女性倡议:实施和评估创新干预措施以提高艾滋病毒护理的参与度和留存率。
Am J Public Health. 2017 Feb;107(2):224-229. doi: 10.2105/AJPH.2016.303582.
5
Understanding Cross-Sectional Racial, Ethnic, and Gender Disparities in Antiretroviral Use and Viral Suppression Among HIV Patients in the United States.了解美国艾滋病毒患者在抗逆转录病毒药物使用和病毒抑制方面的横断面种族、民族和性别差异。
Medicine (Baltimore). 2016 Mar;95(13):e3171. doi: 10.1097/MD.0000000000003171.
6
Vital Signs: Estimated Percentages and Numbers of Adults with Indications for Preexposure Prophylaxis to Prevent HIV Acquisition--United States, 2015.生命体征:2015 年美国有指征进行暴露前预防以预防艾滋病毒感染的成年人的估计百分比和人数。
MMWR Morb Mortal Wkly Rep. 2015 Nov 27;64(46):1291-5. doi: 10.15585/mmwr.mm6446a4.
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HIV prevention: integrating biomedical and behevioral interventions.艾滋病病毒预防:整合生物医学和行为干预措施。
Top Antivir Med. 2014;22(5):702-6.
8
Reaching the unreached: treatment as prevention as a workable strategy to mitigate HIV and its consequences in high-risk groups.惠及未被触及者:治疗即预防作为减轻高危人群中艾滋病毒及其后果的可行策略。
Curr HIV/AIDS Rep. 2014 Dec;11(4):505-12. doi: 10.1007/s11904-014-0238-4.
9
The impact of patient race on clinical decisions related to prescribing HIV pre-exposure prophylaxis (PrEP): assumptions about sexual risk compensation and implications for access.患者种族对与开具 HIV 暴露前预防 (PrEP) 相关的临床决策的影响:关于性风险补偿的假设及其对获取途径的影响。
AIDS Behav. 2014 Feb;18(2):226-40. doi: 10.1007/s10461-013-0675-x.
10
Antiretroviral prophylaxis for HIV infection in injecting drug users in Bangkok, Thailand (the Bangkok Tenofovir Study): a randomised, double-blind, placebo-controlled phase 3 trial.在曼谷泰国注射吸毒者中预防艾滋病毒感染的抗逆转录病毒预防(曼谷替诺福韦研究):一项随机、双盲、安慰剂对照的 3 期临床试验。
Lancet. 2013 Jun 15;381(9883):2083-90. doi: 10.1016/S0140-6736(13)61127-7. Epub 2013 Jun 13.

在城市社区卫生中心与使用艾滋病毒暴露前预防(PrEP)相关的人口统计学特征。

Demographic characteristics associated with the use of HIV pre-exposure prophylaxis (PrEP) in an urban, community health center.

作者信息

Caponi Mitchell, Burgess Carolyne, Leatherwood Alexandra, Molano Luis Freddy

机构信息

Community Healthcare Network, New York, NY, United States of America.

New York University, New York, NY, United States of America.

出版信息

Prev Med Rep. 2019 May 14;15:100889. doi: 10.1016/j.pmedr.2019.100889. eCollection 2019 Sep.

DOI:10.1016/j.pmedr.2019.100889
PMID:31194089
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6551550/
Abstract

Individuals who are at high risk of contracting HIV should have equitable access to preventive measures, such as pre-exposure prophylaxis (PrEP). We conducted a retrospective data extract from the electronic medical records of federally-qualified health centers in New York City from 2016 to 2018. Descriptive statistics are presented, stratified by those who have been prescribed PrEP and those who have not. We created a variable called "ever-female" which includes individuals assigned female at birth or who have ever identified as female. A chi-square test was performed to determine the statistical significance between variables as p < .05. A total of 9659 patients met inclusion criteria for the study. Patients who were prescribed PrEP were significantly associated with being white and never-female, with 38.2% of those prescribed PrEP identifying as white and 83.8% of those prescribed PrEP categorized as never-female. Patients of trans experience were 9.6% of the PrEP cohort and 1.5% of the never PrEP cohort (p < .001). Patients identifying as Black/African American made up 19.8% of patients prescribed PrEP and 49.8% of those never prescribed PrEP (p < .001). Patients with the lowest reported income composed 48.4% of those prescribed PrEP compared to 69.3% of patients who were never prescribed PrEP (p < .001). These findings indicate that key demographic categories may not be accessing PrEP as much as would be expected for their level of risk. Barriers to access of PrEP for women and other at-risk, under-represented populations should be further studied.

摘要

感染艾滋病毒风险较高的个体应能公平地获得预防措施,如暴露前预防(PrEP)。我们对纽约市2016年至2018年联邦合格健康中心的电子病历进行了回顾性数据提取。给出了描述性统计数据,按是否开具PrEP进行分层。我们创建了一个名为“曾经为女性”的变量,包括出生时被指定为女性或曾自认为女性的个体。进行卡方检验以确定变量之间的统计学显著性,p<0.05。共有9659名患者符合该研究的纳入标准。开具PrEP的患者与白人及从未为女性显著相关,开具PrEP的患者中有38.2%为白人,开具PrEP的患者中有83.8%被归类为从未为女性。有跨性别经历的患者在PrEP队列中占9.6%,在未使用PrEP队列中占1.5%(p<0.001)。自认为是黑人/非裔美国人的患者在开具PrEP的患者中占19.8%,在未开具PrEP的患者中占49.8%(p<0.001)。报告收入最低的患者在开具PrEP的患者中占48.4%,而在从未开具PrEP的患者中占69.3%(p<0.001)。这些发现表明,关键人口类别可能没有按照其风险水平预期的那样充分获得PrEP。应进一步研究女性和其他高危、代表性不足人群获得PrEP的障碍。