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将艾滋病病毒暴露前预防(PrEP)纳入常规预防性医疗保健以避免加剧差异。

Integrating HIV Preexposure Prophylaxis (PrEP) Into Routine Preventive Health Care to Avoid Exacerbating Disparities.

作者信息

Calabrese Sarah K, Krakower Douglas S, Mayer Kenneth H

机构信息

Sarah K. Calabrese is with the Department of Psychology, George Washington University, Washington, DC. Douglas S. Krakower and Kenneth H. Mayer are with the Fenway Institute, Boston, MA, and the Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston.

出版信息

Am J Public Health. 2017 Dec;107(12):1883-1889. doi: 10.2105/AJPH.2017.304061. Epub 2017 Oct 19.

Abstract

More than 3 decades since its emergence in the United States, HIV continues to spread and disproportionately affect socially marginalized groups. Preexposure prophylaxis (PrEP), a highly effective prevention strategy federally approved since 2012, could fundamentally alter the course of the epidemic. However, PrEP's potential has not been fully realized, in part because health care providers have been slow to adopt PrEP in clinical practice and have been selective in their discussion of PrEP with patients. This nonstandardized approach has constrained PrEP access. PrEP access has not only been inadequate but also inequitable, with several groups in high need showing lower rates of uptake than do their socially privileged counterparts. Recognizing these early warning signs that current approaches to PrEP implementation could exacerbate existing HIV disparities, we call on health professionals to integrate PrEP into routine preventive health care for adult patients-particularly in primary care, reproductive health, and behavioral health settings. Drawing on the empirical literature, we present 4 arguments for why doing so would improve access and access equity, and we conclude that the benefits clearly outweigh the challenges.

摘要

自在美国出现以来的30多年里,艾滋病毒仍在继续传播,且对社会边缘化群体的影响尤为严重。暴露前预防(PrEP)是一项自2012年起获得联邦批准的高效预防策略,它可能会从根本上改变这一流行病的发展进程。然而,PrEP的潜力尚未得到充分发挥,部分原因是医疗服务提供者在临床实践中采用PrEP的速度较慢,且在与患者讨论PrEP时有所选择。这种不规范的做法限制了PrEP的可及性。PrEP的可及性不仅不足,而且不公平,一些有高度需求的群体的接受率低于社会地位优越的同龄人。认识到当前PrEP实施方法可能会加剧现有艾滋病毒差异的这些早期预警信号,我们呼吁卫生专业人员将PrEP纳入成年患者的常规预防性医疗保健中,特别是在初级保健、生殖健康和行为健康环境中。借鉴实证文献,我们提出了这样做将改善可及性和可及性公平性的4个理由,并得出结论,其好处显然大于挑战。

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