Institute of Polymer Science and Engineering, School of Chemical Engineering and Technology, Hebei University of Technology, Tianjin 300130, China.
National Institute for Materials Science (NIMS), 1-2-1 Sengen, Tsukuba 305-0047, Japan.
J Nanosci Nanotechnol. 2019 Dec 1;19(12):7574-7583. doi: 10.1166/jnn.2019.16740.
Nanodiamonds have gained considerable attention nowadays owing to their excellent properties and various applications especially in biomedical field. Nevertheless, the tendency of agglomeration limits further wide applications of nanodiamonds. A biological method was conducted to graft natural amino acids and ascorbic acid on the surface of nanodiamonds. The results of Fourier transform infrared, Raman spectra, Thermogravimetric analysis and X-ray photoelectron spectroscopy indicate that the biomolecules were covalently boned on the nanodiamonds surface. Moreover, dynamic light scattering particle size analyzer and Transmission electron microscopic were conducted to investigate the particle size and morphology of surface modified nanodiamonds, which implies that nanodiamonds functionalized by biomolecules present smaller particle size, less aggregation and stable dispersion in organic solution and aqueous solution as well as phosphate buffer. This may enlarge the applications of nanodiamonds especially in biological area.
纳米金刚石由于其优异的性能和广泛的应用而备受关注，特别是在生物医学领域。然而，纳米金刚石的团聚倾向限制了其更广泛的应用。本研究采用生物方法将天然氨基酸和抗坏血酸接枝到纳米金刚石表面。傅里叶变换红外光谱、拉曼光谱、热重分析和 X 射线光电子能谱的结果表明，生物分子通过共价键键合到纳米金刚石表面。此外，通过动态光散射粒度分析仪和透射电子显微镜研究了表面修饰纳米金刚石的粒径和形貌，结果表明，生物分子功能化的纳米金刚石在有机溶剂和水溶液以及磷酸盐缓冲液中具有更小的粒径、更少的团聚和更稳定的分散性。这可能会扩大纳米金刚石的应用范围，特别是在生物领域。
