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基孔肯雅热病毒感染在热带环境下的军事部署中——一个叙述性的简要综述。

Chikungunya Virus Infections in Military Deployments in Tropical Settings-A Narrative Minireview.

机构信息

Department of Microbiology and Hospital Hygiene, Bundeswehr Hospital Hamburg, 22049 Hamburg, Germany.

Institute for Medical Microbiology, Virology and Hygiene, University Medicine Rostock, 18057 Rostock, Germany.

出版信息

Viruses. 2019 Jun 14;11(6):550. doi: 10.3390/v11060550.

Abstract

Chikungunya fever is a vector-borne viral disease in subtropical and tropical areas of endemicity. Apart from the burden on local populations, chikungunya virus infection also poses a risk for travelers and, in particular, soldiers during prolonged deployment-associated outdoor activities. The absence of rapid diagnostic tests makes surveillance challenging during military deployments in war and crisis zones with restricted medical infrastructure. Consequently, both historical and up-to-date surveillance data from battlefields are scarce. From several studies and postdeployment assessments, some information on the epidemiology of chikungunya virus infections in deployed military personnel is nevertheless available. The few published data homogeneously suggest a low infection risk in the endemic setting. During outbreaks, however, the infection risk of military personnel is comparable to that of the local population. Infection clusters of soldiers without pronounced outdoor activity have been reported under such circumstances as well. In spite of efforts focusing on the development of a chikungunya virus vaccine, no licensed product is available so far.

摘要

基孔肯雅热是一种发生在地方性流行的亚热带和热带地区的虫媒病毒性疾病。除了给当地居民带来负担外,基孔肯雅病毒感染也对旅行者构成风险,特别是在长期部署相关的户外活动中对士兵构成风险。由于缺乏快速诊断检测,在医疗基础设施有限的战争和危机地区进行军事部署时,监测工作具有挑战性。因此,战场上的历史和最新监测数据都很稀缺。尽管从几项研究和部署后评估中,获得了一些关于部署军事人员中基孔肯雅病毒感染的流行病学信息。但是,少数已发表的数据一致表明,在地方性流行地区感染风险较低。然而,在暴发期间,军事人员的感染风险与当地人群相当。在这种情况下,也有报告称没有明显户外活动的士兵出现感染集群。尽管专注于开发基孔肯雅病毒疫苗的努力,但迄今为止尚无许可产品。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/193b/6631184/d068be578908/viruses-11-00550-g001.jpg

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