Gad Emad Hamdy, Zakaria Hazem, Kamel Yasmin, Alsebaey Ayman, Zakareya Talat, Abbasy Mohamed, Mohamed Anwar, Nada Ali, Abdelsamee Mohammed Alsayed, Housseni Mohamed
Hepatobiliary Surgery, National Liver Institute, Menoufia University, Shebein Elkoum, Egypt.
Anaesthesia, National Liver Institute, Menoufia University, Shebein Elkoum, Egypt.
Ann Med Surg (Lond). 2019 May 31;43:52-63. doi: 10.1016/j.amsu.2019.05.007. eCollection 2019 Jul.
For complicated common bile duct stones (CBDS) that cannot be extracted by endoscopic retrograde cholangiopancreatography (ERCP), management can be safely by open or laparoscopic CBD exploration (CBDE). The study aimed to assess these surgical procedures after endoscopic failure.
We analyzed 85 patients underwent surgical management of difficult CBDS after ERCP failure, in the period from 2013 to 2018.
Sixty-seven (78.8%) and 18(21.2%) of our patients underwent single and multiple ERCP sessions respectively. An impacted large stone was the most frequent cause of ERCP failure (60%). Laparoscopic CBDE(LCBDE), open CBDE(OCBDE) and the converted cases were 24.7% (n = 21), 70.6% (n = 60), and 4.7% (n = 4) respectively. Stone clearance rate post LCBDE and OCBDE reached 95.2% and 95% respectively, Eleven (12.9%) of our patients had postoperative complications without mortality. By comparing LCBDE and OCBDE; there was a significant association between the former and longer operative time. On comparing, T-tube and 1ry CBD closure in both OCBDE and LCBDE, there was significantly longer operative time, and post-operative hospital stays in the former. Furthermore, in OCBDE group, choledocoscopy had an independent direction to 1ry CBD repair and significant association with higher stone clearance rate, shorter operative time, and post-operative hospital stay.
Large difficult CBDS can be managed either by open surgery or laparoscopically with acceptable comparable outcomes with no need for multiple ERCP sessions due to their related morbidities; furthermore, Open choledocoscopy has a good impact on stone clearance rate with direction towards doing primary repair that is better than T-tube regarding operative time and post-operative hospital stay.
对于无法通过内镜逆行胰胆管造影术(ERCP)取出的复杂胆总管结石(CBDS),可通过开放或腹腔镜胆总管探查术(CBDE)进行安全处理。本研究旨在评估内镜治疗失败后的这些外科手术。
我们分析了2013年至2018年期间85例ERCP失败后接受困难CBDS手术治疗的患者。
我们的患者中,分别有67例(78.8%)和18例(21.2%)接受了单次和多次ERCP治疗。结石嵌顿是ERCP失败的最常见原因(60%)。腹腔镜CBDE(LCBDE)、开放CBDE(OCBDE)及中转病例分别占24.7%(n = 21)、70.6%(n = 60)和4.7%(n = 4)。LCBDE和OCBDE术后结石清除率分别达到95.2%和95%。我们的患者中有11例(12.9%)出现术后并发症,但无死亡病例。比较LCBDE和OCBDE;前者与手术时间较长有显著关联。比较OCBDE和LCBDE中T管和一期胆总管闭合情况,前者手术时间明显更长,术后住院时间也更长。此外,在OCBDE组中,术中胆道镜检查对一期胆总管修复有独立指导作用,且与更高的结石清除率、更短的手术时间和术后住院时间显著相关。
大型困难CBDS可通过开放手术或腹腔镜手术进行处理,两者疗效相当,且由于其相关并发症,无需多次进行ERCP;此外,开放术中胆道镜检查对结石清除率有良好影响,指导进行一期修复,在手术时间和术后住院时间方面优于T管引流。