唾液氟保留：含氟咀嚼棒与非草药含氟牙膏的比较分析

Salivary Fluoride Retention: A Comparative Analysis between Fluoride Containing Chewing Sticks and a Non Herbal Fluoridated Toothpaste.

作者信息

Emeke Uwadia, Obontu Taiwo J, Olushola Ibiyemi, Akinyele Adisa

机构信息

Department of Family Dentistry, Faculty of Dentistry, College of Medicine, University of Ibadan, Ibadan, Nigeria, Phone: 08051642991,

Department of Periodontology and Community Dentistry, Faculty of Dentistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.

出版信息

J Contemp Dent Pract. 2019 Mar 1;20(3):370-376.

PMID:31204331

Abstract

AIM

To determine and compare salivary fluoride retention after the use of different fluoride-containing chewing sticks and a non-herbal fluoridated toothpaste.

MATERIALS AND METHODS

This double-blind cross-over experimental study was undertaken among twenty randomly selected senior secondary students in Ibadan, Nigeria. Saliva samples were collected to establish baseline fluoride concentration before the use of chewing sticks and non-herbal fluoridated toothpaste. Four commonly used chewing sticks and one non-herbal fluoridated toothpaste were each used at two days interval, and saliva samples were collected at 0, 10, 30, 45 and 60 minutes after each use. These samples were stored and transported in Gio'Style coolers to the laboratory, where they were analyzed for fluoride concentration using a spectrophotometer at a wavelength of 620 nm. Data were analyzed using descriptive and inferential statistics at < 0.05.

RESULT

At baseline mean (± SD) salivary fluoride concentration of participants was 25.95 (± 4.58) ppm. The mean (± SD) salivary fluoride concentration at 0 minutes was 228.0 (± 032.80) ppm, 427.65 (± 122.85) ppm, 413.45 (± 78.08) ppm, 329.05 (± 83.12) ppm and 323.80 (± 66.41) ppm corresponding to Alchornea laxiflora, Zanthoxylum zanthoxyloides, Anogeissus leocarpus, Masularia acuminate and non-herbal toothpaste respectively. At 60 minutes Zanthoxylum zanthoxyloides had the highest mean (± SD) fluoride concentration of 44.75 (± 13.32) ppm. The differences in mean (± SD) salivary fluoride concentrations amongst these tooth cleaning aids at 60 minutes were statistically significant ( < 0.001).

CONCLUSION

Zanthoxylum zanthoxyloides had the highest mean (± SD) salivary fluoride retention followed by the non-herbal fluoridated toothpaste.

CLINICAL SIGNIFICANCE

The use of chewing sticks can be a cost-effective and efficient means of caries prevention if used properly at regular interval.

摘要

目的

测定并比较使用不同含氟咀嚼棒和一种非草本含氟牙膏后唾液中氟的潴留情况。

材料与方法

本双盲交叉实验研究在尼日利亚伊巴丹随机选取的20名高中生中进行。在使用咀嚼棒和非草本含氟牙膏前收集唾液样本以确定基线氟浓度。四种常用咀嚼棒和一种非草本含氟牙膏每隔两天依次使用一次，每次使用后0、10、30、45和60分钟收集唾液样本。这些样本在Gio'Style冷却器中储存并运至实验室，在实验室使用分光光度计于波长620nm处分析氟浓度。数据采用描述性和推断性统计学方法进行分析，检验水准为<0.05。

结果

参与者基线时唾液氟浓度均值（±标准差）为25.95（±4.58）ppm。0分钟时唾液氟浓度均值（±标准差）分别为：非洲山麻杆228.0（±32.80）ppm、两面针427.65（±122.85）ppm、红厚壳413.45（±78.08）ppm、尖叶马桑329.05（±83.12）ppm以及非草本牙膏323.80（±66.41）ppm。60分钟时，两面针的唾液氟浓度均值（±标准差）最高，为44.75（±13.32）ppm。这些口腔清洁辅助用品在60分钟时唾液氟浓度均值（±标准差）的差异具有统计学意义（<0.001）。