Centro Javeriano de Oncología - Hospital Universitario San Ignacio - Bogotá, Colombia.
Prevention and Implementation Group - International Agency for Research on Cancer - Lyon, France.
Biomed Res Int. 2019 May 7;2019:9607803. doi: 10.1155/2019/9607803. eCollection 2019.
Implementation of evidence-based cancer prevention and early detection in low- and middle-income countries (LMIC) is challenging. Limited and inappropriate introduction of novel alternatives results in an equity gap whereby low-income populations receive a lower benefit. Implementation research represents an opportunity to foster the adoption and expansion of evidence-based cancer control strategies; however, scientific development in high-income countries does not necessarily fulfill the particular needs of LMIC in the field. A review on the link between implementation research and practice, the tension between theory and pragmatism, the conflict around implementation research methods, and determinants of research priority definition was carried out by considering the perspective of cancer prevention and early detection implementers in LMIC. Basic principles and alternatives to overcome implementation research challenges in these settings are discussed.
在中低收入国家（LMIC）实施基于证据的癌症预防和早期检测具有挑战性。新型替代方案的引入有限且不恰当，导致公平性差距，使低收入人群受益较低。实施研究代表了促进采用和扩大基于证据的癌症控制策略的机会；然而，高收入国家的科学发展不一定满足该领域中低收入国家的特殊需求。通过考虑中低收入国家癌症预防和早期检测执行者的观点，对实施研究与实践之间的联系、理论与务实之间的紧张关系、实施研究方法的冲突以及研究重点定义的决定因素进行了审查。讨论了在这些环境中克服实施研究挑战的基本原则和替代方案。
