Monocyte changes in cancer patients and their role in mitogen induced lymphocyte responses.
作者信息
Uracz W, Pituch A, Mytar B, Noworolski J, Zembala M
出版信息
Arch Immunol Ther Exp (Warsz). 1978;26(1-6):429-34.
PMID:312077
Abstract
Monocyte Fc receptor expression and monocyte-mediated antibody dependent cell cytotoxicity (ADCC) was studied in a group of patients with stomach and colorectal carcinoma. Is was found that FC receptor expression and ADCC was increased in patients as compared to control subjects. These differences were more evident after trypsin pretreatment of monocytes. There was an inverse correlation between these changes and lymphocyte response to PHA. The role of monocyte functional changes in determining the magnitude of patients' lymphocyte response is discussed.
摘要
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Monocyte changes in cancer patients and their role in mitogen induced lymphocyte responses.
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