环丙沙星和氧氟沙星对鸟分枝杆菌-胞内分枝杆菌复合体的体外活性。
In vitro activity of ciprofloxacin and ofloxacin against the Mycobacterium avium-intracellulare complex.
作者信息
Johnson S M, Roberts G D
机构信息
Department of Laboratory Medicine, Mayo Clinic, Rochester, MN 55905.
出版信息
Diagn Microbiol Infect Dis. 1987 May;7(1):89-91. doi: 10.1016/0732-8893(87)90077-0.
The in vitro activity of ciprofloxacin and ofloxacin against strains of Mycobacterium avium-intracellulare complex were studied by the standard 1% proportion method. Thirty-eight of 100 strains (30%) were inhibited by ciprofloxacin at 2 micrograms/ml and 11 of 30 strains (37%) were inhibited by ofloxacin at 8 microm/ml. Patients having these more susceptible isolates may potentially benefit from therapy with these agents [corrected].
采用标准的1%比例法研究了环丙沙星和氧氟沙星对鸟分枝杆菌-胞内分枝杆菌复合体菌株的体外活性。100株菌株中有38株（30%）在环丙沙星浓度为2微克/毫升时被抑制，30株菌株中有11株（37%）在氧氟沙星浓度为8微克/毫升时被抑制。感染这些更易被药物抑制的菌株的患者可能会从这些药物的治疗中获益[已修正]。
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