Gevaudan M J, Mallet M N, Gulian C, Terriou P, Lagier P, de Micco P
Laboratoire de Microbiologie, Hygiène et Epidémiologie Hospitalière, Hôpital Salvator, Marseille.
Pathol Biol (Paris). 1988 May;36(5):477-81.
The authors have tested the sensibility to three new quinolones of forty one strains of mycobacteria belonging to seven different species. They have observed, in particular, susceptibility for the species M. tuberculosis, M. fortuitum, M. kansasii, M. marinum and M. xenopi to ciprofloxacin and ofloxacin and a limited sensibility for these same species to pefloxacin. In association with others antibiotics, amikacin, erythromycin, thienamycin, trimethoprim-sulfamethoxazole, the three have shown some additive effects and in a few cases synergistic effects.
作者检测了属于7个不同种的41株分枝杆菌对3种新喹诺酮类药物的敏感性。他们特别观察到，结核分枝杆菌、偶然分枝杆菌、堪萨斯分枝杆菌、海分枝杆菌和蟾蜍分枝杆菌对环丙沙星和氧氟沙星敏感，而对培氟沙星的敏感性有限。与其他抗生素（阿米卡星、红霉素、硫霉素、甲氧苄啶-磺胺甲恶唑）联合使用时，这3种喹诺酮类药物均显示出一些相加作用，在少数情况下还有协同作用。
