Texier-Maugein J, Mormède M, Fourche J, Bébéar C
Laboratoire de Bactériologie, Hôpital Xavier-Arnozan, Pessac, Bordeaux, France.
Eur J Clin Microbiol. 1987 Oct;6(5):584-6. doi: 10.1007/BF02014255.
The in vitro activity of pefloxacin, norfloxacin, ofloxacin and ciprofloxacin against 86 strains of mycobacteria was evaluated by broth dilution. While Mycobacterium avium, Mycobacterium scrofulaceum and Mycobacterium chelonae were resistant to all four antibacterials, the susceptibility of the other species, Mycobacterium tuberculosis, Mycobacterium kansasii, Mycobacterium xenopi and Mycobacterium fortuitum, depended on the antibiotic. Ofloxacin and ciprofloxacin (MIC90: 0.5 - 2 mg/l) were more active than pefloxacin and norfloxacin (MIC90: 2 - 16 mg/l).
采用肉汤稀释法评估了培氟沙星、诺氟沙星、氧氟沙星和环丙沙星对86株分枝杆菌的体外活性。鸟分枝杆菌、瘰疬分枝杆菌和龟分枝杆菌对这四种抗菌药物均耐药，而其他菌种，如结核分枝杆菌、堪萨斯分枝杆菌、偶发分枝杆菌和嗜肺分枝杆菌的药敏情况则取决于抗生素种类。氧氟沙星和环丙沙星（MIC90：0.5 - 2mg/L）比培氟沙星和诺氟沙星（MIC90：2 - 16mg/L）活性更强。
