Liu Chang-Jun, Zhao Yunjun, Zhang Kewei
Department of Biology, Brookhaven National Laboratory, Upton, NY, United States.
Department of Biology, College of Chemistry and Life Sciences, Zhejiang Normal University, Jinhua, China.
Front Plant Sci. 2019 May 31;10:693. doi: 10.3389/fpls.2019.00693. eCollection 2019.
Cytokinins (CKs) are a group of mobile adenine derivatives that act as chemical signals regulating a variety of biological processes implicated in plant development and stress responses. Their synthesis, homeostasis, and signaling perception evoke complicated intracellular traffic, intercellular movement, and in short- and long-distance translocation. Over nearly two decades, subsets of membrane transporters have been recognized and implicated in the transport of CKs as well as the related adenylates. In this review, we aim to recapitulate the key progresses in exploration of the transporter proteins involved in cytokinin traffic and translocation, discuss their functional implications in the cytokinin-mediated paracrine and long-distance communication, and highlight some knowledge gaps and open issues toward comprehensively understanding the molecular mechanism of membrane transporters in controlling spatiotemporal distribution of cytokinin species.
细胞分裂素（CKs）是一类可移动的腺嘌呤衍生物，作为化学信号调节与植物发育和应激反应相关的多种生物学过程。它们的合成、稳态和信号感知引发了复杂的细胞内运输、细胞间移动以及短距离和长距离转运。在近二十年里，已识别出膜转运蛋白的一些亚群，它们参与细胞分裂素以及相关腺苷酸的运输。在本综述中，我们旨在概括细胞分裂素运输和转运相关转运蛋白探索方面的关键进展，讨论它们在细胞分裂素介导的旁分泌和长距离通讯中的功能意义，并强调在全面理解膜转运蛋白控制细胞分裂素种类时空分布的分子机制方面存在的一些知识空白和未解决问题。
