Department of Dermatology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Dermatol Ther. 2019 Sep;32(5):e13001. doi: 10.1111/dth.13001. Epub 2019 Jul 10.
Primary cutaneous nocardiosis caused by Nocardia brasiliensis is an uncommon disease. The present authors report a Chinese woman presented with lymphocutaneous nocardiosis caused by N. brasiliensis. The lesion begin with her right hand after an unknown insect sting and evolved rapidly and formed painful erythema and two subcutaneous nodules and abscesses on her right forearm in 5 days. N. brasiliensis was isolated from pustule and identified by gene sequencing. The patient received 2 weeks of combination therapy contained infusion of amoxilin potassioum clavinet and oral TMP/SMX and followed by a single therapy of oral TMP/SMX for 1 month and got a marked improvement. The present authors reviewed a case of lymphocutaneous nocardiosis caused by N. brasiliensis reported in China.
巴西奴卡菌引起的原发性皮肤奴卡菌病较为少见。本文报告 1 例中国女性患者,因巴西奴卡菌引起的淋巴管皮肤奴卡菌病。患者右手于 5 天前被不明昆虫叮咬后出现病变,迅速进展为右前臂疼痛性红斑和 2 个皮下结节和脓肿。巴西奴卡菌从脓疱中分离培养,并通过基因测序鉴定。患者接受 2 周的阿莫西林克拉维酸钾静脉滴注和口服复方磺胺甲噁唑联合治疗,随后改为口服复方磺胺甲噁唑单药治疗 1 个月,病情明显改善。本文复习了中国报道的 1 例巴西奴卡菌引起的淋巴管皮肤奴卡菌病。