Department of Nutrition, Taiwan Adventist Hospital, Taipei, Taiwan.
Department of Neurology, Taiwan Adventist Hospital, Taipei, Taiwan.
PLoS One. 2019 Jun 20;14(6):e0218749. doi: 10.1371/journal.pone.0218749. eCollection 2019.
BACKGROUND & OBJECTIVE: Malnutrition is one of commonly issues in patients with stroke. The Mini Nutritional Assessment (MNA) is a widely used measure for assessing nutritional status in patients with stroke. A nutritional measure with acceptable test-retest reliability allows clinicians to consistently assess patients' nutritional status. Knowledge of the relationship between nutritional status and quality of life (QOL) could guide clinicians to improve QOL in patients with stroke more effectively. This study aimed to examine test-retest reliability of the MNA and its relationship with QOL in patients with stroke.
Fifty-nine patients participated in the test-retest reliability study and the correlation between the MNA and WHO Quality of Life-BREF (WHOQOL-BREF) study. A repeated-assessments design (1 week apart) was used to examine the test-retest reliability of the MNA.
The intraclass correlation coefficient for the MNA was 0.91. The minimal detectable change and percentage of minimal detectable change for the MNA were 2.1 and 8.2%, respectively. The MNA was positively associated with the QOL (r = 0.32; p = 0.013). The result of linear regression analysis shows that after controlling for age, sex and activities of daily living functions, only the MNA was significantly associated with the WHOQOL-BREF (r2 = 0.104; p = 0.008).
The MNA has satisfactory test-retest reliability that is useful for repeatedly assessing the nutritional status of patients with stroke. The MDC of the MNA has acceptable random measurement error which is useful for determining whether the change score of a patient is outside the range of random measurement error. Future studies that recruit stroke patients in the acute stage is needed to further examine the relationship between the nutritional status and QOL.
营养不良是脑卒中患者常见的问题之一。微型营养评估（MNA）是评估脑卒中患者营养状况的常用方法。具有可接受的重测信度的营养测量方法可以使临床医生能够持续评估患者的营养状况。了解营养状况与生活质量（QOL）之间的关系可以指导临床医生更有效地提高脑卒中患者的生活质量。本研究旨在检验 MNA 的重测信度及其与脑卒中患者生活质量的关系。
59 名患者参加了重测信度研究和 MNA 与世界卫生组织生活质量简表（WHOQOL-BREF）研究的相关性。采用重复评估设计（间隔 1 周）来检验 MNA 的重测信度。
MNA 的组内相关系数为 0.91。MNA 的最小可检测变化和最小可检测变化百分比分别为 2.1 和 8.2%。MNA 与 QOL 呈正相关（r = 0.32；p = 0.013）。线性回归分析结果表明，在控制年龄、性别和日常生活活动功能后，只有 MNA 与 WHOQOL-BREF 显著相关（r2 = 0.104；p = 0.008）。
MNA 具有令人满意的重测信度，可用于反复评估脑卒中患者的营养状况。MNA 的 MDC 具有可接受的随机测量误差，可用于确定患者的变化得分是否超出随机测量误差范围。需要在急性阶段招募脑卒中患者的进一步研究，以进一步检验营养状况与 QOL 之间的关系。
