Bloedon Taylor K, Braithwaite Rock E, Carson Imogene A, Klimis-Zacas Dorothy, Lehnhard Robert A
Department of Kinesiology and Recreation Administration, Humboldt State University, Arcata, California, USA.
School of Food and Agriculture, University of Maine, Orono, Maine, USA.
Nutr Rev. 2019 Sep 1;77(9):630-645. doi: 10.1093/nutrit/nuz018.
Supplementing with fruits high in anthocyanins to reduce exercise-induced oxidative stress and inflammation has produced mixed results.
This systematic review and meta-analysis aims to discuss the impact of whole fruits high in anthocyanins, including processing methods and the type and amount of fruit, on inflammation and oxidative stress.
PICOS reporting guidelines and a customized coding scheme were used to search 5 databases (SPORTDiscus, Science Direct, Web of Science [BIOSIS], Medline [Pubmed], and the Cochrane Collaboration) with additional cross-referencing selection.
A random-effects meta-analysis was used to measure effects of the fruit supplements with 3 statistics; the QTotal value based on a χ2 distribution, τ2 value, and I2 value were used to determine homogeneity of variances on 22 studies (out of 807). Outliers were identified using a relative residual value.
A small significant negative summary effect across the sum of all inflammatory marker outcomes (P < 0.001) and a moderate negative effect for the sum of all oxidative stress marker outcomes (P = 0.036) were found. Moderator analyses did not reveal significant (P > 0.05) differences between subgrouping variables.
Results indicate that consumption of whole fruit high in anthocyanins can be beneficial for reducing inflammation and oxidative stress.
补充富含花青素的水果以减轻运动诱导的氧化应激和炎症，结果不一。
本系统评价和荟萃分析旨在探讨富含花青素的完整水果，包括加工方法、水果类型和数量，对炎症和氧化应激的影响。
采用PICOS报告指南和定制编码方案检索5个数据库（SPORTDiscus、Science Direct、Web of Science [BIOSIS]、Medline [Pubmed]和Cochrane协作网），并进行额外的交叉引用筛选。
采用随机效应荟萃分析，用3种统计量测量水果补充剂的效果；基于χ2分布的QTotal值、τ2值和I2值用于确定807项研究中22项研究的方差齐性。使用相对残差值识别异常值。
发现所有炎症标志物结果总和有小的显著负向汇总效应（P < 0.001），所有氧化应激标志物结果总和有中度负向效应（P = 0.036）。调节因素分析未显示亚组变量之间有显著差异（P > 0.05）。
结果表明，食用富含花青素的完整水果可能有助于减轻炎症和氧化应激。
