Jakob J, Hohenberger P
Klinik für Allgemein‑, Viszeral- und Kinderchirurgie, Universitätsmedizin Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Deutschland.
Sektion Chirurgische Onkologie und Thoraxchirurgie, Chirurgische Klinik, Universitätsmedizin Mannheim, Th.-Kutzer-Ufer 1-3, 68163, Mannheim, Deutschland.
Pathologe. 2019 Jul;40(4):431-435. doi: 10.1007/s00292-019-0631-2.
Soft-tissue sarcomas are rare malignant tumors. Surgery remains the most important treatment modality. Neoadjuvant and/or adjuvant chemo- and radiotherapy may be administered to improve the local and systemic outcome. Advances in oncological and reconstructive surgery, combined with the use of multimodal therapies, have made mutilating surgery rare events in extremity sarcomas. In retroperitoneal sarcomas, local recurrences are life-threatening events and multivisceral resection has become the standard surgical procedure. The subjects of this review are diagnostics, multimodal therapy, and resection strategy from a surgical point of view.
软组织肉瘤是罕见的恶性肿瘤。手术仍然是最重要的治疗方式。可进行新辅助和/或辅助化疗及放疗以改善局部和全身治疗效果。肿瘤学和重建外科的进展，结合多模式治疗的应用，已使肢体肉瘤的致残性手术很少发生。在腹膜后肉瘤中，局部复发是危及生命的事件，多脏器切除已成为标准的外科手术。本综述的主题是从外科角度探讨诊断、多模式治疗和切除策略。
