2019 年 2 月，从中国四川和山东的猪肉中检测到质粒介导的替加环素耐药基因（X4）。
Detection of plasmid-mediated tigecycline-resistant gene (X4) in from pork, Sichuan and Shandong Provinces, China, February 2019.
机构信息
Key Laboratory of Food Safety Risk Assessment, National Health Commission of the People's Republic of China, Beijing, People's Republic of China.
Food Safety Research Unit of Chinese Academy of Medical Sciences, China National Center for Food Safety Risk Assessment, Beijing, People's Republic of China.
出版信息
Euro Surveill. 2019 Jun;24(25). doi: 10.2807/1560-7917.ES.2019.24.25.1900340.
The plasmid-mediated high-level tigecycline resistance gene, (X4), was detected in seven isolates from pork in two Chinese provinces. Two isolates belonged to the epidemic spreading sequence type ST101. (X4) was adjacent to IS and concurrent with in all seven isolates. In addition to IncFIB, the replicon IncFII was found to be linked to (X4). This report follows a recent detection of (X3)/(X4) in from animals and humans in China.
质粒介导的高水平替加环素耐药基因（X4）在来自中国两个省份猪肉中的 7 个分离株中被检测到。两个分离株属于流行传播的 ST101 序列型。（X4）位于 IS 附近，与所有 7 个分离株中的 同时存在。除 IncFIB 外，还发现（X4）与 IncFII 复制子相连。本报告是继最近在中国的动物和人类中检测到（X3）/（X4）之后的又一发现。
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