Wynder E L
American Health Foundation, New York City, NY 10017.
Public Health Rep. 1988 Jan-Feb;103(1):8-18.
The suspicion that the use of tobacco adversely affects health existed for some time before a case-control study appeared in 1950 of 684 cases of lung cancer strongly associated with cigarette smoking. This paper, a brief history, describes the background of the 1950 landmark study as well as other pertinent epidemiologic and experimental studies of the 1950s and 1960s. This body of research provided evidence for the causative association between tobacco use and lung cancer and other chronic diseases such as several other types of cancer and coronary heart disease. Despite this body of evidence, support from scientists, health professionals, and government officials on the issue of smoking and health came slowly. The scientific application of this discovery to prevent tobacco-linked diseases continues to be far more difficult than the discoveries themselves. Thus, although the low-yield cigarette has provided some assistance to smokers, smoking prevention is far more important, and greater efforts are needed to achieve cessation, particularly among women and minority groups. Beyond this approach, efforts to prevent children and young people from beginning to smoke should stress State-mandated school health education beginning in the earliest grades. The Know Your Body School Education Program, which includes an annual screening with the results entered into a personalized Health Passport starting in first grade, has demonstrated reductions in onset of smoking as well as improved health behavior in nutrition. To further reduce tobacco use, cancer prevention units staffed by health educators, behavioral scientists, and epidemiologists should practice prevention on a communitywide basis. The prevention of diseases as the ultimate aim of medicine and science can be demonstrated by the smoking and health issue that establishes that the prevention of many cancers is attainable.
在1950年一项针对684例与吸烟密切相关的肺癌病例的病例对照研究出现之前,人们对烟草使用会对健康产生不利影响的怀疑已经存在了一段时间。本文是一篇简史,描述了1950年这项具有里程碑意义的研究的背景以及20世纪50年代和60年代的其他相关流行病学和实验研究。这一系列研究为烟草使用与肺癌以及其他慢性疾病(如其他几种癌症和冠心病)之间的因果关系提供了证据。尽管有这一系列证据,但科学家、健康专业人员和政府官员在吸烟与健康问题上的支持来得很缓慢。将这一发现科学地应用于预防与烟草相关的疾病,仍然比这些发现本身要困难得多。因此,尽管低焦油香烟对吸烟者有一定帮助,但预防吸烟更为重要,需要做出更大努力来实现戒烟,尤其是在女性和少数群体中。除此之外,防止儿童和年轻人开始吸烟的努力应强调从最早年级开始实施国家规定的学校健康教育。“了解你的身体”学校教育项目,包括从一年级开始每年进行一次筛查,并将结果录入个性化的健康护照,已显示出吸烟率有所降低,同时营养方面的健康行为也有所改善。为了进一步减少烟草使用,由健康教育工作者、行为科学家和流行病学家组成的癌症预防单位应在社区范围内开展预防工作。作为医学和科学最终目标的疾病预防,可以通过吸烟与健康问题得到证明,该问题表明预防多种癌症是可以实现的。