G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Vladivostok, Russian Federation.
Far Eastern Federal University, Vladivostok, Russian Federation.
Nat Prod Res. 2021 Jan;35(1):131-134. doi: 10.1080/14786419.2019.1610954. Epub 2019 Jun 26.
Nine naphto-γ-pyrones rubrofusarine B (), TMC 256 A1 (), fansecinones A () and B (), aurasperones A (), B () and F (), dianhydro-aurasperone C () and asperpyrone B () were isolated from the marine-derived fungus KMM 4694. Their structures were established based on spectroscopic methods. The effect of the substances on viability and colony formation of human drug-resistant prostate cancer 22Rv1 cell was evaluated.
从海洋来源真菌 KMM 4694 中分离得到了 9 个萘基-γ-色酮 rubrofusarine B ()、TMC 256 A1 ()、fansecinones A () 和 B ()、aurasperones A ()、B () 和 F ()、二氢-aurasperone C () 和 asperpyrone B ()。基于光谱方法确定了这些物质的结构。评估了这些物质对人耐药前列腺癌 22Rv1 细胞活力和集落形成的影响。
