Center for Innovative Research for Communities and Clinical Excellence (CiRC2LE), Fukushima Medical University, Fukushima, Japan.
You Home Clinic, Tokyo, Japan.
J Clin Hypertens (Greenwich). 2019 Jul;21(7):942-949. doi: 10.1111/jch.13593. Epub 2019 Jun 26.
As few epidemiological studies have investigated the effect of lifestyle factors on hypertension in the very elderly population, we conducted a cross-sectional study to examine the association of estimated salt intake and body weight with blood pressure in the very elderly population. We enrolled 288 participants aged 75 years or older who were residents of Sukagawa City, Fukushima Prefecture, Japan, who attended the health checkup conducted in 2015. Salt intake was estimated from spot urine samples using the Tanaka method. The mean values for age, estimated salt intake, and body weight of all participants were 79.7 years, 9.1 g/d (standard deviation 2.4 g), and 54.3 kg (standard deviation 10.2 kg), respectively. General linear models showed that salt intake and body weight were associated with higher systolic blood pressure (SBP) levels (per standard deviation higher level, adjusted difference 4.13 mm Hg [95% confidence interval 1.69-6.57] and 5.34 mm Hg [95% confidence interval 2.12-8.56], respectively). Body weight was associated with higher diastolic blood pressure (DBP) levels (per standard deviation higher level, 2.74 mm Hg [95% confidence interval 0.58-4.90]). However, salt intake was not associated with higher diastolic blood pressure levels (per standard deviation higher level, 1.15 mm Hg [95% confidence interval -0.49 to 2.79]). Our findings suggest that higher SBP is associated with both salt intake and body weight and that higher DBP is associated with body weight in the very elderly population. This study provides a rationale for lifestyle modifications to prevent hypertension as a population approach.
由于很少有流行病学研究调查生活方式因素对超高龄人群高血压的影响,我们进行了一项横断面研究,以检查超高龄人群的估计盐摄入量和体重与血压之间的关系。我们招募了 288 名年龄在 75 岁或以上的参与者,他们是日本福岛县须贺川市的居民,参加了 2015 年进行的健康检查。盐摄入量是通过田中法从随机尿液样本中估计的。所有参与者的年龄、估计盐摄入量和体重的平均值分别为 79.7 岁、9.1g/d(标准差 2.4g)和 54.3kg(标准差 10.2kg)。一般线性模型显示,盐摄入量和体重与更高的收缩压(SBP)水平相关(每标准偏差更高水平,调整差异为 4.13mmHg[95%置信区间 1.69-6.57]和 5.34mmHg[95%置信区间 2.12-8.56])。体重与更高的舒张压(DBP)水平相关(每标准偏差更高水平,2.74mmHg[95%置信区间 0.58-4.90])。然而,盐摄入量与更高的舒张压水平无关(每标准偏差更高水平,1.15mmHg[95%置信区间-0.49 至 2.79])。我们的研究结果表明,较高的 SBP 与盐摄入量和体重均相关,而较高的 DBP 与超高龄人群的体重相关。这项研究为通过生活方式改变来预防高血压提供了一个理论依据,这是一种针对人群的方法。