Scientific Tobacco Institute Prilep, St. Kliment Ohridski University of Bitola, Prilep, North Macedonia.
Faculty of Pharmacy, Ss. Cyril and Methodius University in Skopje, Skopje, North Macedonia.
Arh Hig Rada Toksikol. 2019 Jun 1;70(2):130-133. doi: 10.2478/aiht-2019-70-3191.
The use of electronic cigarettes or vaping has been gaining momentum among Macedonian smokers but has also raised great many concerns about the toxicity of liquid refills and its aerosols, especially as the nicotine levels in refill liquids (e-liquids) are not required to be declared accurately or at all by current regulations. The aim of this study was therefore to determine nicotine levels in fifteen samples of e-liquids purchased in specialised shops in Macedonia using gas chromatography. Nicotine concentrations deviated from manufacturer's declarations in nine of the twelve samples: in five they were higher and in four lower than declared, ranging from -16.7 % to +30.0 %. These significant discrepancies between the actual and declared nicotine concentrations in the analysed e-liquids call for closer attention of the healthcare and the regulating authorities.
电子烟或蒸气烟在马其顿烟民中越来越流行，但也引起了人们对液体补充剂和其气溶胶毒性的极大关注，尤其是因为补充液（电子烟液）的尼古丁含量目前不受法规要求准确或根本不申报。因此，本研究的目的是使用气相色谱法测定在马其顿专门商店购买的十五个电子烟液样本中的尼古丁含量。在十二种样本中的九种中，尼古丁浓度与制造商的声明不符：五种样本的浓度高于声明，四种低于声明，范围在-16.7%至+30.0%之间。在分析的电子烟液中，实际和申报的尼古丁浓度之间存在这些显著差异，需要医疗保健和监管当局更加关注。
