Stuart-Taylor M E, Sleigh J W
Shackleton Department of Anaesthetics, Southampton General Hospital.
Anaesthesia. 1987 Nov;42(11):1218-22. doi: 10.1111/j.1365-2044.1987.tb05234.x.
Three different dosage regimens of alfentanil were compared with boluses of fentanyl in 80 patients who underwent a variety of surgical procedures. Alfentanil given by infusion at a rate of 7.5 micrograms/kg/minute for 10 minutes followed by 0.75 micrograms/kg/minute, was shown to provide a stable anesthetic which minimises the use of a volatile agent for surgery that lasts more than 45 minutes.
在80例接受各种外科手术的患者中，将三种不同剂量方案的阿芬太尼与芬太尼推注进行了比较。结果显示，以7.5微克/千克/分钟的速率输注阿芬太尼10分钟，然后以0.75微克/千克/分钟的速率输注，可提供稳定的麻醉效果，将持续超过45分钟的手术中挥发性麻醉剂的使用降至最低。
