Wei Tao-Yang, Hsueh Pang-Hsin, Wen Shu-Hui, Chen Chien-Lin, Wang Chia-Chi
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan.
School of Medicine, Tzu Chi University, Hualien, Taiwan.
Tzu Chi Med J. 2019 Jul-Sep;31(3):169-176. doi: 10.4103/tcmj.tcmj_48_18.
The incidence of gastroesophageal reflux disease (GERD) is increasing, and the disease has a close association with dietary habits. This study aims to investigate the role of tea and coffee drinking in the development of GERD.
This study prospectively enrolled individuals who underwent an upper gastrointestinal endoscopy during a health checkup. Each participant completed the reflux disease questionnaire (RDQ). Coffee or tea drinking was defined as drinking the beverage at least 4 days/week for 3 months. Heavy coffee or tea consumption was defined as drinking at least two cups every day.
A total of 1837 participants (970 men; age 51.57 ± 10.21 years), who had data on clinical characteristics and consumption of coffee and tea with or without additives such as milk or sugar were included for final analysis. Among them, 467 (25.4%) were diagnosed as having symptomatic GERD based on the RDQ score, and 427 (23.2%) had erosive esophagitis (EE) on endoscopy. Drinking coffee or tea was not associated with reflux symptoms or EE in univariate and multivariate analyses. In contrast, drinking coffee with milk was associated with reflux symptoms and drinking "tea and coffee" was associated with EE in univariate analysis. However, these associations became insignificant after multivariate analysis.
Drinking coffee or tea and adding milk or sugar was not associated with reflux symptoms or EE.
胃食管反流病(GERD)的发病率正在上升,且该疾病与饮食习惯密切相关。本研究旨在探讨饮用茶和咖啡在GERD发病中的作用。
本研究前瞻性纳入了在健康体检期间接受上消化道内镜检查的个体。每位参与者完成反流病问卷(RDQ)。咖啡或茶的饮用定义为每周至少饮用4天,持续3个月。大量饮用咖啡或茶定义为每天至少饮用两杯。
共有1837名参与者(970名男性;年龄51.57±10.21岁)纳入最终分析,这些参与者有关于临床特征以及饮用含或不含牛奶或糖等添加剂的咖啡和茶的相关数据。其中,根据RDQ评分,467名(25.4%)被诊断为有症状的GERD,427名(23.2%)在内镜检查中有糜烂性食管炎(EE)。在单因素和多因素分析中,饮用咖啡或茶与反流症状或EE均无关联。相比之下,在单因素分析中,加牛奶饮用咖啡与反流症状相关,饮用“茶和咖啡”与EE相关。然而,在多因素分析后,这些关联变得不显著。
饮用咖啡或茶以及添加牛奶或糖与反流症状或EE无关。