Wearne Nicola, Okpechi Ikechi G, Swanepoel Charles R
Division of Nephrology and Hypertension, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.
Kidney and Hypertension Research Unit, University of Cape Town, Cape Town, South Africa.
Kidney Dis (Basel). 2019 Jun;5(3):189-196. doi: 10.1159/000497324. Epub 2019 Mar 22.
South Africa (SA) is an upper middle-income country with a human immunodeficiency virus (HIV) epidemic, an accelerated burden of non-communicable diseases, and a concurrent epidemic of tuberculosis. These con-ditions overwhelm a health system struggling under the pressure of restricted resources, including an insufficient workforce. Private practice has become more involved in the care of patients in the country but serves mainly those who are members of a Medical Aid. These Medical Aids will usually cover up to 100% of the costs for management of chronic kidney disease (CKD).
There are currently 2.3 nephrologists per million individuals, which is far lower than the global average and grossly inadequate to meet the nephrology care needs in SA. Covert chronic dialysis rationing has occurred in the public sector since the 1960s. However, the lack of formality triggered the formation of explicit rationing guidelines in one province. These guidelines have been ethically endorsed but not embraced nationally. The demand for hemodialysis (HD) has led some provinces to practicing "PD-First" programs. SA remains one of only 12 countries within Africa that perform renal transplantation, and it is the only country in Africa that relies on deceased donation for the majority of its transplants. The first kidney transplant in SA took place at the University of the Witwatersrand, Johannesburg, in 1966 and the first dialysis was performed by a general practitioner working in a town close to Johannesburg in 1957. The University of Cape Town successfully pioneered the transplantation of kidneys from HIV-positive donors to positive recipients. SA was the second country in the world to form a National Kidney Foundation as well as a renal society. Nephrology training is in place and incorporates master's and PhD programs in nephrology. Despite the numerous challenges, SA nephrologists have been among the leading researchers in nephrology from the African continent.
南非是一个上中等收入国家,面临着人类免疫缺陷病毒(HIV)流行、非传染性疾病负担加速以及结核病并发流行的问题。这些情况使本就因资源有限(包括劳动力不足)而不堪重负的卫生系统雪上加霜。私人执业在该国患者护理中发挥了更大作用,但主要服务于医疗援助计划的成员。这些医疗援助计划通常会支付慢性肾脏病(CKD)管理费用的100%。
目前每百万人口中有2.3名肾脏病学家,这远低于全球平均水平,严重不足以满足南非的肾脏病护理需求。自20世纪60年代以来,公共部门就出现了隐性慢性透析配给情况。然而,由于缺乏规范性,一个省份制定了明确的配给指南。这些指南在伦理上得到了认可,但尚未在全国范围内得到采用。对血液透析(HD)的需求促使一些省份实施“优先腹膜透析”计划。南非仍然是非洲仅有的12个进行肾移植的国家之一,并且是非洲唯一一个大多数移植依赖尸体捐赠的国家。南非的首例肾移植于1966年在约翰内斯堡的威特沃特斯兰德大学进行,首例透析由一名在约翰内斯堡附近城镇工作的全科医生于1957年完成。开普敦大学成功开创了将HIV阳性供体的肾脏移植给阳性受体的先河。南非是世界上第二个成立国家肾脏基金会和肾脏学会的国家。肾脏病学培训已经到位,包括肾脏病学硕士和博士项目。尽管面临诸多挑战,南非的肾脏病学家一直是非洲大陆肾脏病学领域的领先研究者。