Laugesen Nicolaj Grønbæk, Stenør Christian
Ugeskr Laeger. 2019 Jul 1;181(27).
This is a case report of a 68-year-old woman, who developed malaise after an insect bite. Symptoms subsided, and over weeks progressing difficulty with walking, ataxia and universal areflexia developed. A lumbar puncture showed mononuclear pleocytosis and moderately raised protein levels with no detected viral agents. An MRI of the spinal cord showed leptomeningeal contrast attenuation distally. Serum samples were positive for anti-tick-borne encephalitis (TBE) IgM-antibodies, but not IgG, and showed seroconversion. TBE is endemic in areas of Central Europe and Scandinavia but has earlier only been shown in the eastern part of Denmark.
这是一例68岁女性的病例报告，她在被昆虫叮咬后出现不适。症状消退，数周后逐渐出现行走困难、共济失调和全身无反射。腰椎穿刺显示单核细胞增多以及蛋白水平中度升高，未检测到病毒病原体。脊髓磁共振成像显示远端软脑膜对比剂衰减。血清样本抗蜱传脑炎（TBE）IgM抗体呈阳性，但IgG抗体阴性，并显示血清转化。TBE在中欧和斯堪的纳维亚地区流行，但此前仅在丹麦东部有病例报道。
