British Columbia Centre on Substance Use, Vancouver, Canada.
Department of Family Medicine, University of British Columbia, Vancouver, Canada.
Addict Sci Clin Pract. 2019 Jul 3;14(1):23. doi: 10.1186/s13722-019-0153-5.
North America is in the midst of an opioid overdose epidemic. Although take-home naloxone and other measures have been an effective strategy to reduce overdoses, many events are unwitnessed and mortality remains high amongst those using drugs alone. While wearable devices that can detect and alert others of an overdose are being developed, willingness of people who use drugs to wear such a device has not been described.
Drug using persons enrolled in a community-recruited cohort in Vancouver, Canada, were asked whether or not they would be willing to wear a device against their skin that would alert others in the event of an overdose. Logistic regression was used to identify factors independently associated with willingness to wear such a device.
Among the 1061 participants surveyed between December 2017 and May 2018, 576 (54.3%) were willing to wear an overdose detection device. Factors independently associated with willingness included ever having overdosed (adjusted odds ratio [AOR] = 1.39, 95% confidence interval [CI] 1.06-1.83), current methadone treatment (AOR = 1.86, 95% CI 1.45-2.40), female gender AOR = 1.41, 95% CI 1.09-1.84) and a history of chronic pain (AOR = 1.53, 95% CI 1.19-1.96). Whereas homelessness (AOR = 0.67, 95% CI 0.50-0.91) was negatively associated with willingness.
A high level of willingness to wear an overdose detection device was observed in this setting and a range of factors associated with overdose were positively associated with willingness. Since some factors, such as homelessness may be a barrier, further research is needed to investigate explanations for unwillingness and to evaluate real world acceptability of a wearable overdose detection devices as this technology becomes available.
北美洲正处于阿片类药物过量流行之中。尽管携带纳洛酮回家和其他措施已成为减少过量的有效策略，但许多事件无人目睹，独自使用毒品的人死亡率仍然很高。虽然正在开发可以检测和提醒他人过量的可穿戴设备，但尚未描述使用毒品的人对佩戴此类设备的意愿。
在加拿大温哥华的一个社区招募的队列中招募了吸毒者，询问他们是否愿意在发生过量时佩戴贴在皮肤上的设备来提醒他人。使用逻辑回归来确定与佩戴此类设备的意愿独立相关的因素。
在 2017 年 12 月至 2018 年 5 月期间调查的 1061 名参与者中，有 576 名（54.3％）愿意佩戴过量检测设备。与愿意佩戴设备独立相关的因素包括曾经过量（调整后的优势比[OR]＝1.39，95％置信区间[CI]为 1.06-1.83），当前美沙酮治疗（OR ＝1.86，95％CI 为 1.45-2.40），女性（OR ＝1.41，95％CI 为 1.09-1.84）和慢性疼痛史（OR ＝1.53，95％CI 为 1.19-1.96）。而无家可归（OR ＝0.67，95％CI 为 0.50-0.91）与佩戴意愿呈负相关。
在这种情况下，观察到对佩戴过量检测设备的高度意愿，并且与过量相关的一系列因素与佩戴意愿呈正相关。由于某些因素（例如无家可归）可能是一个障碍，因此需要进一步研究不愿佩戴的原因，并评估可穿戴式过量检测设备在现实世界中的可接受性，因为这项技术即将面世。
