Schaadt O, Bohr H
Department of Internal Medicine TTA, Rigshospitalet, University of Copenhagen, Denmark.
Calcif Tissue Int. 1988 Feb;42(2):71-6. doi: 10.1007/BF02556337.
The bone mineral content (BMC) was measured by dual photon absorptiometry of 153Gd simultaneously in the lumbar spine, femoral neck, and femoral shaft in a cross-sectional study of 113 healthy women aged 20-89 years. The measurements suggest differences in the patterns of bone mineral decrease at the three sites of the skeleton in relation to age. The lumbar spine BMC decreases mainly during the usual time of menopause, whereas BMC decreases linearly in the femoral neck from young adulthood to old age. The femoral shaft BMC is nearly unaltered until the seventh decade, and thereafter BMC declines significantly. In each of the three age groups selected according to the usual time for menopause there was significant correlations between BMC of the scanning sites and nearly identical variance of BMC with age, suggesting homogeneity in the female population with regard to rate of bone diminution.
在一项针对113名年龄在20至89岁的健康女性的横断面研究中，采用双能光子吸收法同时测量了她们腰椎、股骨颈和股骨干的骨矿物质含量（BMC）及153Gd。测量结果表明，骨骼三个部位的骨矿物质减少模式随年龄存在差异。腰椎BMC主要在绝经通常发生的时间段内下降，而股骨颈BMC从青年期到老年期呈线性下降。股骨干BMC在七十岁之前几乎没有变化，此后BMC显著下降。在根据绝经通常时间划分的三个年龄组中，各扫描部位的BMC之间存在显著相关性，且BMC随年龄的变化方差几乎相同，这表明女性群体在骨质减少速率方面具有同质性。
