Łukaszewska-Kuska Magdalena, Krawczyk Piotr, Martyla Agnieszka, Hędzelek Wiesław, Dorocka-Bobkowska Barbara
Department of Gerodontology and Oral Pathology, Poznan University of Medical Sciences, Poland.
Institute of Chemistry and Technical Electrochemistry, Poznan University of Technology, Poland.
Dent Med Probl. 2019 Apr-Jun;56(2):123-129. doi: 10.17219/dmp/103851.
A dental implant surface which would promote rapid and strong osseointegration is a key factor of success in modern implantology. To achieve this goal, different implant surface modifications are developed. A hydroxyapatite (HA) coating changing a bioinert titanium surface into bioactive is one of them.
The objective of the study was to investigate the effects on bone osseointegration in rabbits resulting from the application of a HA coating deposited on titanium endosseous implants using a modified electrochemical method.
Titanium implants with HA coatings and controls with Al2O3 grit-blasted surfaces were embedded into rabbit tibiae. The chemical composition, roughness and morphology of the implants were determined. Implant stability tests were performed, and the Periotest® value (PTV) and the implant stability quotient (ISQ) value for Osstell Mentor were recorded in order to evaluate the osseointegration.
The surface characterization of the implants revealed a microstructure with an arithmetical mean height (Sa) in the range of 0.71-1.04 μm. The HA coating was free of contamination, whereas the controls were enriched with corundum. After healing, a statistically significant increase in the mean ISQ and a decrease in the mean PTV for the HA-coated implants was observed. In the case of the control implants, only PTV decreased significantly with time.
The present study found that implant surface properties affected implant stability as determined by Osstell and Periotest measurements. The HA coating reported herein was found to have chemical and physical properties which appear to improve osseointegration compared to grit-blasted implants.
在现代种植牙学中，能促进快速且牢固骨结合的牙种植体表面是成功的关键因素。为实现这一目标，人们研发了不同的种植体表面改性方法。将生物惰性钛表面转变为生物活性表面的羟基磷灰石（HA）涂层就是其中之一。
本研究旨在调查采用改良电化学方法在钛骨内种植体上沉积HA涂层对兔骨骨结合的影响。
将带有HA涂层的钛种植体以及经Al2O3喷砂处理表面的对照种植体植入兔胫骨。测定种植体的化学成分、粗糙度和形态。进行种植体稳定性测试，并记录Periotest®值（PTV）和Osstell Mentor的种植体稳定性商数（ISQ）值，以评估骨结合情况。
种植体的表面特征显示其微观结构的算术平均高度（Sa）在0.71 - 1.04μm范围内。HA涂层无污染，而对照种植体富含刚玉。愈合后，观察到HA涂层种植体的平均ISQ有统计学意义的增加，平均PTV降低。对于对照种植体，只有PTV随时间显著降低。
本研究发现，如通过Osstell和Periotest测量所确定的，种植体表面特性会影响种植体稳定性。本文报道的HA涂层具有化学和物理特性，与喷砂处理的种植体相比，似乎能改善骨结合。
