Morris Timothy P, Tormos Muñoz Jose-Maria, Cattaneo Gabriele, Solana-Sánchez Javier, Bartrés-Faz David, Pascual-Leone Alvaro
Institut Guttmann, Institut Universitari de Neurorehabilitació Adscrit a la UAB, Badalona, Spain.
Universitat Autònoma de Barcelona, Bellaterra, Spain.
Front Behav Neurosci. 2019 Jun 19;13:135. doi: 10.3389/fnbeh.2019.00135. eCollection 2019.
Physical activity has many health benefits for individuals with and without history of brain injury. Here, we evaluated in a large cohort study the impact of physical activity on global and cognitive health as measured by the PROMIS global health and NeuroQoL cognitive function questionnaires. A nested case control study assessed the influence of a history of traumatic brain injury (TBI) on the effects of physical activity since underlying pathophysiology and barriers to physical activity in individuals with TBI may mean the effects of physical activity on perceived health outcomes differ compared to the general population. Those with a history of TBI ( = 81) had significantly lower Global health ( = -1.66, = 0.010) and NeuroQoL cognitive function ( = -2.65, = 0.006) compared to healthy adults ( = 405). A similar proportion of individuals in both groups reported being active compared to being insufficiently active ( = 0.519 = 0.471). Furthermore, the effect of physical activity on global health ( = 0.061, = 0.076) and particularly for NeuroQoL ( = 0.159, = 0.002) was greater in those with a history of TBI. Individuals with a history of TBI can adhere to a physically active lifestyle, and if so, that is associated with higher global and cognitive health perceptions. Adhering to a physically active lifestyle is non-trivial, particularly for individuals with TBI, and therefore adapted strategies to increase participation in physical activity is critical for the promotion of public health.
体育活动对有或没有脑损伤病史的个体都有许多健康益处。在此，我们在一项大型队列研究中评估了体育活动对通过PROMIS全球健康和NeuroQoL认知功能问卷测量的整体和认知健康的影响。一项巢式病例对照研究评估了创伤性脑损伤（TBI）病史对体育活动效果的影响，因为TBI个体的潜在病理生理学和体育活动障碍可能意味着体育活动对感知健康结果的影响与一般人群不同。与健康成年人（n = 405）相比，有TBI病史的人（n = 81）的全球健康得分（β = -1.66，P = 0.010）和NeuroQoL认知功能得分（β = -2.65，P = 0.006）显著更低。两组中报告活跃的个体比例与报告活动不足的个体比例相似（P = 0.519，P = 0.471）。此外，体育活动对有TBI病史的人的全球健康（β = 0.061，P = 0.076）尤其是对NeuroQoL（β = 0.159，P = 0.002）的影响更大。有TBI病史的个体可以坚持积极的生活方式，如果这样做，这与更高的整体和认知健康感知相关。坚持积极的生活方式并非易事，尤其是对于TBI个体，因此采用适应性策略来增加体育活动参与度对于促进公众健康至关重要。
