Miller H R, Nawa Y, Parish C R
Int Arch Allergy Appl Immunol. 1979;59(3):281-5. doi: 10.1159/000232271.
Adoptive immunization of Nippostrongylus-infected rats augmented goblet cell differentiation in the intestinal epithelium. After fractionation of immune thoracic duct lymphocytes (TDL), cells lacking surface immunoglobulin (sIg-) were the most potent stimulators of goblet cell differentiation. Moreover, TDL drained from rats harbouring a primary infection were more effective than TDL from hyperimmune rats.
对感染类圆线虫的大鼠进行过继免疫可增强肠上皮中杯状细胞的分化。对免疫胸导管淋巴细胞(TDL)进行分级分离后,缺乏表面免疫球蛋白(sIg-)的细胞是杯状细胞分化的最有效刺激物。此外,来自患有原发性感染大鼠的引流TDL比来自超免疫大鼠的TDL更有效。