Ng S K, Au E, Thirumoorthy T
Middle Road Hospital, Singapore.
Ann Acad Med Singap. 1987 Oct;16(4):645-7.
In a retrospective study of ophthalmia neonatorum seen in Middle Road Hospital between 1983 and 1986, 68% were caused by Neisseria gonorrhoeae. 40% of the Neisseria gonorrhoeae isolates were PPNG strains. For therapy of gonococcal ophthalmia neonatorum, 1% kanamycin eyedrops combined with a single intramuscular injection of kanamycin or a third generation Cephalosporin (Ceftriaxone or Cefotaxime) were all effective regimens. The use of intramuscular kanamycin was stopped because of concern for ototoxicity. Chlamydia trachomatis remains an uncommon cause of ophthalmia neonatorum in Singapore, in only 2 cases was this agent identified.
在一项对1983年至1986年间中路医院收治的新生儿眼炎的回顾性研究中，68%的病例由淋病奈瑟菌引起。40%的淋病奈瑟菌分离株为产青霉素酶的淋病奈瑟菌（PPNG）菌株。对于新生儿淋菌性眼炎的治疗，1%卡那霉素滴眼液联合单次肌内注射卡那霉素或第三代头孢菌素（头孢曲松或头孢噻肟）均为有效的治疗方案。由于担心耳毒性，已停止使用肌内注射卡那霉素。沙眼衣原体仍是新加坡新生儿眼炎的罕见病因，仅发现2例由该病原体引起。
