单剂量卡那霉素治疗新生儿淋菌性眼炎及生理盐水眼部冲洗

Management of gonococcal ophthalmia neonatorum with single-dose kanamycin and ocular irrigation with saline.

作者信息

Latif A, Mason P, Marowa E, Paraiwa E, Dhamu F, Tambo J, Gwanzura L, Mapeta D, Jongeling G

机构信息

Harare City Health Department, University of Zimbabwe.

出版信息

Sex Transm Dis. 1988 Apr-Jun;15(2):108-9. doi: 10.1097/00007435-198804000-00008.

DOI:10.1097/00007435-198804000-00008

PMID:3135607

Abstract

Two hundred nineteen neonates with gonococcal ophthalmia neonatorum, including 40 infected with penicillinase-producing strains, were treated as outpatients with a single intramuscular injection of 100 mg of kanamycin and hourly ocular irrigation with saline. Neisseria gonorrhoeae was isolated from three (1.4%) of the 212 babies attending for follow-up, and post-gonococcal conjunctivitis developed in 22 (10.4%) of those who returned for follow-up.

摘要

219例患有新生儿淋菌性眼炎的新生儿，其中40例感染产青霉素酶菌株，作为门诊患者接受单次100mg卡那霉素肌肉注射，并每小时用生理盐水冲洗眼部。在前来随访的212名婴儿中，有3例（1.4%）分离出淋病奈瑟菌，在前来随访的婴儿中有22例（10.4%）发生了淋菌性结膜炎后结膜炎。