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训练诱导的神经可塑性和强度在中风后会增强。

Training-Induced Neural Plasticity and Strength Are Amplified After Stroke.

机构信息

Rehabilitation Neuroscience Laboratory, University of Victoria, Victoria, BC.

Human Discovery Science, International Collaboration on Repair Discovery (ICORD), Vancouver, BC.

出版信息

Exerc Sport Sci Rev. 2019 Oct;47(4):223-229. doi: 10.1249/JES.0000000000000199.

DOI:10.1249/JES.0000000000000199
PMID:31283528
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6887626/
Abstract

Following stroke, sensorimotor brain networks and descending regulation are compromised but spinal interlimb neural connections remain morphologically intact. After cross-education strength and locomotion training, amplified neural plasticity and functional responses are observed in chronic stroke compared with neurologically intact participants. We hypothesize that poststroke neuroplasticity is amplified because of the involvement of interlimb neural connections that persist from our quadrupedal ancestry.

摘要

中风后,感觉运动脑网络和下行调节受损,但脊髓肢体间神经连接在形态上保持完整。交叉教育力量和运动训练后,与神经完整的参与者相比,慢性中风患者观察到增强的神经可塑性和功能反应。我们假设中风后的神经可塑性增强是因为涉及到从四足动物祖先那里延续下来的肢体间神经连接。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f817/6887626/5687453b7201/jes-47-223-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f817/6887626/be5fcbc43402/jes-47-223-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f817/6887626/e965a2e581d3/jes-47-223-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f817/6887626/46f8401d6565/jes-47-223-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f817/6887626/5687453b7201/jes-47-223-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f817/6887626/be5fcbc43402/jes-47-223-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f817/6887626/e965a2e581d3/jes-47-223-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f817/6887626/46f8401d6565/jes-47-223-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f817/6887626/5687453b7201/jes-47-223-g004.jpg

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The Spinal Transcriptome after Cortical Stroke: In Search of Molecular Factors Regulating Spontaneous Recovery in the Spinal Cord.皮质卒中后的脊髓转录组:寻找调节脊髓自发性恢复的分子因素。
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