Department of Ophthalmology, University of Health Sciences, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, İstanbul, Turkey.
Curr Eye Res. 2019 Dec;44(12):1381-1385. doi: 10.1080/02713683.2019.1639766. Epub 2019 Aug 2.
: To quantify and compare the foveal avascular zone (FAZ) and the whole, parafoveal and foveal vessel density of superficial (SCP) and deep capillary plexus (DCP) in amblyopic eyes of adults and age-matched controls.: This cross-sectional study involved 52 eyes from 34 subjects aged 18 to 45 years. Optical coherence tomography angiography (OCTA) was performed to all participants and SCP, DCP and FAZ were evaluated. SPSS (Statistical Package for the Social Sciences) 23 was used for data analysis.: Eighteen of 34 subjects (52,9%) were amblyopic and 16 (47,1%) of them controlled. Mean subject age was 31.2 years in the amblyopia group and 28.3 years in the control group. The mean FAZ measurements were 0.28 ± 0.08 in amblyopic eyes, 0.29 ± 0.08 in fellow eyes and 0.3 ± 0.11 in control eyes. The whole, foveal and parafoveal vessel density of SCP in both 3x3-mm and 6x6-mm scans were not statistically different in amblyopic eyes, fellow eyes and control eyes. In 6x6-mm scans, the whole, and parafoveal vessel density of DCP were significantly lower in amblyopic eyes than controls. There was no statistically significant difference in 3x3-mm scans about DCP.: OCTA revealed lower vessel density in DCP of amblyopic eyes than fellow eyes and controls in adults.
: 定量比较成人弱视眼和年龄匹配对照组的浅层（SCP）和深层毛细血管丛（DCP）的中心凹无血管区（FAZ）和整体、旁中心凹和中心凹血管密度。：本横断面研究纳入了 34 名年龄在 18 至 45 岁的受试者的 52 只眼。对所有参与者进行光学相干断层扫描血管造影（OCTA）检查，评估 SCP、DCP 和 FAZ。采用 SPSS（社会科学统计软件包）23 进行数据分析。：34 名受试者中有 18 名（52.9%）为弱视，其中 16 名（47.1%）为对照组。弱视组的平均年龄为 31.2 岁，对照组为 28.3 岁。弱视眼的平均 FAZ 测量值为 0.28 ± 0.08，对侧眼为 0.29 ± 0.08，对照组为 0.3 ± 0.11。在 3x3mm 和 6x6mm 扫描中，SCP 的整体、中心凹和旁中心凹血管密度在弱视眼、对侧眼和对照组之间均无统计学差异。在 6x6mm 扫描中，弱视眼的 DCP 整体和旁中心凹血管密度明显低于对照组。在 3x3mm 扫描中，DCP 无统计学差异。：OCTA 显示成人弱视眼的 DCP 血管密度低于对侧眼和对照组。
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