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蛋白质、黏蛋白和人泪液对铜绿假单胞菌黏附亲水性隐形眼镜的影响。

Effects of protein, mucin, and human tears on adherence of Pseudomonas aeruginosa to hydrophilic contact lenses.

作者信息

Miller M J, Wilson L A, Ahearn D G

机构信息

Laboratory for Microbial and Biochemical Sciences, Georgia State University, Atlanta 30303.

出版信息

J Clin Microbiol. 1988 Mar;26(3):513-7. doi: 10.1128/jcm.26.3.513-517.1988.

Abstract

Pseudomonas aeruginosa isolated from a corneal ulcer was examined for its ability to adhere to hydrophilic contact lenses with adsorbed organic films. Generally, adherence was enhanced by mucin, lactoferrin, lysozyme, immunoglobulin A, bovine serum albumin, and a mixture of these macromolecules. The water content of the lenses also influenced bacterial adherence and protein adsorption. Adherence to lenses coated with human tear films was more complex; both enhanced and inhibited adherence were observed on lenses obtained from different individuals.

摘要

对从角膜溃疡中分离出的铜绿假单胞菌进行了检测,以评估其附着于带有吸附有机膜的亲水性隐形眼镜的能力。一般来说,粘蛋白、乳铁蛋白、溶菌酶、免疫球蛋白A、牛血清白蛋白以及这些大分子的混合物会增强细菌的附着。镜片的含水量也会影响细菌附着和蛋白质吸附。细菌附着于涂有人泪膜的镜片的情况更为复杂;在取自不同个体的镜片上,既观察到了附着增强的情况,也观察到了附着受抑制的情况。

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Evolution of soft contact lens coatings.
Arch Ophthalmol. 1980 Jan;98(1):95-9. doi: 10.1001/archopht.1980.01020030097007.
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Corneal ulcers associated with contact lens wear.与隐形眼镜佩戴相关的角膜溃疡
Arch Ophthalmol. 1984 Jun;102(6):891-4. doi: 10.1001/archopht.1984.01040030711025.
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Gram-negative corneal ulcers in elderly aphakic eyes with extended-wear lenses.
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