Department of Pediatric Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Department of Pediatrics, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana.
Pediatr Blood Cancer. 2019 Oct;66(10):e27895. doi: 10.1002/pbc.27895. Epub 2019 Jul 9.
Data regarding micronutrient deficiencies in children with cancer are lacking. We measured micronutrients in a subset of children with cancer (n = 23) participating in a randomized trial of the neutropenic diet. Ninety-six percent of children had ≥1 micronutrient deficiency and 39% had ≥3 micronutrient deficiencies. Eighty-six percent of children had vitamin C deficiency, 87% had 25-hydroxyvitamin D deficiency, 50% had zinc deficiency, and 13% had vitamin A deficiency. Dietary intake did not correlate with micronutrient deficiency status. More data are needed regarding the prevalence and etiology of micronutrient deficiencies in children with cancer to further understand their implications and treatment.
有关癌症儿童微量营养素缺乏的数据尚缺乏。我们测量了参与中性粒细胞减少饮食随机试验的一部分癌症儿童（n = 23）的微量营养素。96%的儿童有≥1 种微量营养素缺乏，39%的儿童有≥3 种微量营养素缺乏。86%的儿童有维生素 C 缺乏，87%的儿童有 25-羟维生素 D 缺乏，50%的儿童有锌缺乏，13%的儿童有维生素 A 缺乏。膳食摄入量与微量营养素缺乏状况无关。需要更多有关癌症儿童微量营养素缺乏的患病率和病因的数据，以进一步了解其影响和治疗。
