使用手性四氧杂杯[2]芳烃[2]三嗪作为有机催化剂，蒽酮与硝基烯烃进行有效的不对称迈克尔加成反应。
Effective asymmetric Michael addition of anthrone to nitroalkenes using chiral tetraoxacalix[2]arene[2]triazines as organocatalysts.
作者信息
Genc Hayriye Nevin
机构信息
Department of Science Education, A. K. Education Faculty, Necmettin Erbakan University, Konya, Turkey.
出版信息
Chirality. 2019 Sep;31(9):711-718. doi: 10.1002/chir.23108. Epub 2019 Jul 11.
PMID:31294902
Abstract
Novel chiral secondary amines bearing a tetraoxacalix[2]arene[2]triazine scaffold were created and used for catalytic asymmetric Michael reaction of anthrone with nitroalkenes. The relevant adducts were obtained in good to excellent yields (82%-98%) and enantioselectivities (75%-98%).
摘要
合成了带有四氧杂杯[2]芳烃[2]三嗪骨架的新型手性仲胺，并将其用于蒽酮与硝基烯烃的催化不对称迈克尔反应。相关加合物的产率良好至优异（82%-98%），对映选择性为75%-98%。
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