Born in Bradford, Bradford Institute for Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford Royal Infirmary, Duckworth Lane, Bradford, BD9 6RJ, UK.
Leeds Teaching Hospitals NHS Trust, Great George Street, Leeds, LS1 3EX, UK.
BMC Public Health. 2019 Jul 12;19(1):939. doi: 10.1186/s12889-019-7222-2.
Born in Bradford (BiB) is a prospective multi-ethnic pregnancy and birth cohort study that was established to examine determinants of health and development during childhood and, subsequently, adult life in a deprived multi-ethnic population in the north of England. Between 2007 and 2010, the BiB cohort recruited 12,453 women who experienced 13,776 pregnancies and 13,858 births, along with 3353 of their partners. Forty five percent of the cohort are of Pakistani origin. Now that children are at primary school, the first full follow-up of the cohort is taking place. The aims of the follow-up are to investigate the determinants of children's pre-pubertal health and development, including through understanding parents' health and wellbeing, and to obtain data on exposures in childhood that might influence future health.
We are employing a multi-method approach across three data collection arms (community-based family visits, school based physical assessment, and whole classroom cognitive, motor function and wellbeing measures) to follow-up over 9000 BiB children aged 7-11 years and their families between 2017 and 2021. We are collecting detailed parent and child questionnaires, cognitive and sensorimotor assessments, blood pressure, anthropometry and blood samples from parents and children. Dual x-ray absorptiometry body scans, accelerometry and urine samples are collected on subsamples. Informed consent is collected for continued routine data linkage to health, social care and education records. A range of engagement activities are being used to raise the profile of BiB and to disseminate findings.
Our multi-method approach to recruitment and assessment provides an efficient method of collecting rich data on all family members. Data collected will enhance BiB as a resource for the international research community to study the interplay between ethnicity, socioeconomic circumstances and biology in relation to cardiometabolic health, mental health, education, cognitive and sensorimotor development and wellbeing.
“生于布拉德福德”（BiB）是一项前瞻性的多民族妊娠和分娩队列研究，旨在研究英格兰北部贫困多民族人群在儿童期和随后的成年期的健康和发展决定因素。在 2007 年至 2010 年期间，BiB 队列招募了 12453 名女性，她们经历了 13776 次妊娠和 13858 次分娩，以及 3353 名伴侣。该队列中有 45%的人是巴基斯坦裔。现在孩子们已经上小学了，该队列正在进行第一次全面随访。随访的目的是调查儿童青春期前健康和发育的决定因素，包括了解父母的健康和幸福状况，并获得可能影响未来健康的儿童期暴露数据。
我们正在通过三个数据收集臂（基于社区的家庭访问、基于学校的身体评估和整个教室认知、运动功能和幸福感测量）采用多方法方法，在 2017 年至 2021 年期间对超过 9000 名年龄在 7-11 岁的 BiB 儿童及其家庭进行随访。我们正在收集详细的父母和儿童问卷、认知和感觉运动评估、父母和儿童的血压、人体测量学和血液样本。对亚组进行双能 X 线吸收仪全身扫描、加速度计和尿液样本采集。收集了知情同意书，以便继续对健康、社会关怀和教育记录进行常规数据链接。正在使用一系列参与活动来提高 BiB 的知名度并传播研究结果。
我们的招募和评估多方法方法为收集所有家庭成员的丰富数据提供了一种有效的方法。收集的数据将增强 BiB 作为国际研究界的资源，用于研究种族、社会经济环境和生物学之间的相互作用与心血管代谢健康、心理健康、教育、认知和感觉运动发育以及幸福感的关系。
