Research Center for Organic Electronics (ROEL), Yamagata University, 4-3-16 Jonan, Yonezawa, Yamagata, 992-8510, Japan.
Sci Rep. 2019 Jul 12;9(1):10102. doi: 10.1038/s41598-019-46611-z.
This study is the first report demonstrating proof-of-concept for a hydrogel-based touch sensor pad used for the non-invasive extraction and detection of sweat components. The sensor device was composed of an electrochemical L-lactate biosensor covered with an agarose gel in a phosphate buffer saline. When human skin contacts the agarose gel, L-lactate in sweat was continuously extracted into the gel, followed by in-situ potentiometric detection without controlled conditions. This novel type of sweat sensor is expected to enable the simple, non-invasive daily periodic monitoring of sweat biomarkers for advanced personal healthcare methods in the future.
本研究首次报告了一种基于水凝胶的触摸传感器垫的概念验证，该传感器垫可用于非侵入式提取和检测汗液成分。该传感器装置由一个电化学 L-乳酸生物传感器组成，该传感器覆盖在琼脂糖凝胶中，置于磷酸盐缓冲盐溶液中。当人体皮肤接触到琼脂糖凝胶时，汗液中的 L-乳酸会不断被提取到凝胶中，然后在无需控制条件的情况下进行原位电位检测。这种新型汗液传感器有望为未来先进的个人医疗保健方法实现简单、非侵入式的日常周期性汗液生物标志物监测。
